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Drug Safety Matters

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Drug Safety Matters

Uppsala Monitoring Centre

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Drug Safety Matters brings you the best stories from the world of pharmacovigilance. Through in-depth interviews with our guests, we cover new research and trends, and explore the most pressing issues in medicines safety today. Produced by Uppsala Monitoring Centre, the WHO Collaborating Centre for International Drug Monitoring.
 
The Community Safety Podcast has been created by Jim Nixon from Birmingham in the United Kingdom. Community Safety is the use of skills, knowledge and techniques, to prevent and reduce crime, disorder and fear of crime and develop safer communities in which to live, work and visit. Community Safety affects us all in society, it's all our responsibility to improve communities. Some of the main issues affecting communities in today’s society is violence, knife crime, mental health, alcohol abu ...
 
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With vaccine hesitancy on the rise and misinformation spreading like wildfire on social media, drug safety specialists may have a hard time knowing how to talk about side effects without affecting people’s trust in vaccinations. Anthony Cox from the University of Birmingham and Daniel Salmon from the Institute for Vaccine Safety share their best ad…
 
It’s not always easy to choose the best medicine for a child. Some drugs are inappropriate for young patients, while others require special consideration or monitoring. For years, clinicians had only historical dogmas, word of mouth and their own experience to guide their choices. But a valuable new resource promises to change paediatric prescribin…
 
CSP20-The drug war in the UK and worldwide has been going on for a long time. It's not new to see news coverage on buy busts and undercover operations. It makes us more aware of the drug problem, but also lulls us into a false sense of security that things are improving. In reality, these drug busts pose more threats to our community safety. In thi…
 
CSP 19-Reforming Lives, Transforming Communities, and Campaigning for Prison Reform with David Breakspear The criminal justice system exists to create better and safer communities for everyone. People who commit serious crimes are sentenced to prison for them to reflect on their actions, and hopefully, come out better. In today’s special episode, w…
 
Fuelled by disinformation and an array of other cultural and economic factors, vaccine hesitancy is one of the greatest global health communication challenges of our times. But to craft the empathetic and tailored communication strategies required to boost confidence in vaccines, we first need to understand the difference between anti-vaccination b…
 
CSP 18-Equipping your loved ones with Open Water safety skills with Beckie Ramsay. Swimming is one of the life skills we are taught at a young age. We learn to manage our breathing and to propel our arms and legs to keep us afloat. However, the open water houses dangers beyond its inviting surface. The water may be too cold. Debris and other object…
 
CSP 17-Episode on Challenging the Norm to Effectively Tackle Anti-Social Behaviour The predicament of anti-social behaviours is not something you turn your back on. Anti-social behaviours have a huge impact not just on individuals, but also in the families and the communities. Today’s episode explores the deep-rooted causes of anti-social behaviour…
 
Genetic variation is one of the reasons people differ in their response to medicines. Understanding that variation can inform more refined choices of drugs and doses – ultimately preventing undesired side effects. Join us as we discuss past, present and future of pharmacogenomics with Uppsala Monitoring Centre’s Qun-Ying Yue. Tune in to find out: H…
 
CSP 16-Understanding Youth Offenders and Youth Exploitation with Nikki Holmes Child exploitation is a serious problem. Many youths are coerced and manipulated to engage in violence, abuse, and criminality. We can be quick to pass judgement on those who get on the wrong side of the law. But the issue of exploitation doesn’t start with the crime and …
 
CSP 15-Finding Success and Lending a Helping Hand with Mark Maciver Life can be pretty harsh, especially when you go through failures and setbacks. When you hit rock bottom, it's hard to see a way out and even harder to lend a helping hand to others. But failure is a phase: it is not permanent. When you lend a helping hand and extend a little bit o…
 
CSP14 - Matt Murray The Power Role Models Hold in Dealing with Racism in Football with Matt Murray Dealing with Racism, Discrimination, and Hate: How Matt Murray Managed to be a Successful Professional Football Player Dealing with Racism through Kindness: Matt Murray's Journey in Professional Football Racism is everywhere, even in professional foot…
 
With COVID-19 vaccinations rolling at full speed in many countries, there’s a lot of talk about vaccine safety monitoring. But what exactly does that mean and how should we be interpreting data on side effects? Uppsala Monitoring Centre’s Helena Sköld and Annette Rudolph walk us through the basics of vaccine pharmacovigilance. Tune in to find out: …
 
CSP13 -The Struggles At Home: Cycles of Domestic Violence with Su Bhuhi MBE Aanchal Women’s Aid was founded by Su Bhuhi when a woman needed support to safeguard her children from being taken to South Asia against her will. Su, a survivor herself, took a stand to help protect the women and her children from further harm. We provide support and servi…
 
CSP12 - John Hayward Cripps John is a former director and interim CEO of Victim Support and has worked for various charities at senior levels across England for over 20 years. John’s aim as CEO of Neighbourhood Watch is to build on the fantastic history and achievements and help the movement move forward to gain new and diverse membership and stren…
 
CSP11 - Carl Chinn MBE Ph.D Carl Chinn, MBA Ph.D. Carl is a social historian with a national profile, a writer, a teacher, an animator, and a public speaker. He was formerly a professor of Community History at the University of Birmingham, and director of Birmingham Lives Project collecting working-class memories as a freelance social historian. He…
 
While COVID-19 vaccinations are picking up speed in many wealthy countries, citizens of lower-income countries still face a long wait ­– and where demand exceeds supply, black markets tend to form. So to curb the spread of substandard and falsified products, says drug regulatory specialist Danini Marin, we must ensure that COVID-19 vaccines are dis…
 
CSP10- Susanne Knabe-Nichol Dr Susanne Knabe-Nichol is an Investigative Psychologist and founder of Police Science Dr. She translates research findings into videos that can easily be understood by those without academic journal subscriptions or a degree in psychology or criminology. She has an MSc and a PhD in Investigative Psychology, and intervie…
 
CSP9 - Alison Cope The biggest trauma Alison Cope has ever faced was losing her son Joshua to knife crime in 2013, but she uses her resilience and strength to educate and support others in seeing a future beyond negative experiences. Alison presents the Joshua Ribera Achievement Awards that recognises and celebrates the achievements of young people…
 
Antimicrobial resistance (AMR) is not only a biological issue, but a complex social problem. As a consequence, changing the way patients, healthcare professionals and policymakers think about antibiotics will require input from both the natural and social sciences. In March 2021, the Uppsala Health Summit on “Managing antimicrobial resistance throu…
 
CSP8 - Sharon Bryan For the last 23 years, Sharon Bryan has worked in the field of domestic abuse. She is also a survivor of domestic abuse. In 2020. Sharon set up Sharon Bryan consultancy, a community interest company which involves running the Freedom Programme for women who have experienced domestic abuse. In January 2021, Sharon joined the awar…
 
CSP7 - Dee Kelly Deirdre "Dee" Kelly, also known as White Dee, is a British TV personality and actor. In 2014 and 2015, she appeared in the TV documentary series Benefits Street, and in 2014 she took part in Celebrity Big Brother. She plays Liz in the 2019 film Ray & Liz, directed by Richard Billingham. In 2014, Kelly spoke at a Policy Exchange fri…
 
As the COVID-19 pandemic spread around the world, so did waves of viral misinformation. For pharmacovigilance manager Marco Tuccori, fighting the “infodemic” is a massive, but necessary, battle. This episode is part of the Uppsala Reports Long Reads series – the most topical stories from UMC’s pharmacovigilance magazine, brought to you in audio for…
 
CSP6 - Caroline Goode Caroline Goode served for 33 years in the Metropolitan Police in London. She retired as a Detective Superintendent in the Counter-Terrorism Command after spending ten years leading more than 100 complex murder investigations. One of those investigations, the so-called honour killing of a young Iraqi Kurdish woman by her family…
 
CSP5 - Nazir Afzal Nazir Afzal OBE was Chief Crown Prosecutor for North West England, and most recently, he was Chief Executive of the country’s Police & Crime Commissioners. During a 24 year career, he has prosecuted some of the most high-profile cases in the country, including the so-called Rochdale grooming gang, and led nationally on several le…
 
By definition, a rare disease is one that only affects a handful of people in the world. But with more than 300 million people collectively affected by these conditions and only few approved treatments available, rare diseases constitute a major unmet medical need. Christina Ström Möller from Swedish biopharmaceutical company Sobi walks us through …
 
CSP4 - John Sutherland John joined the Metropolitan Police in 1992, where he served for 25 years across seven London boroughs in a range of ranks and roles, including as Borough Commander and Chief Superintendent. He published Blue: A Memoir – Keeping The Peace And Falling To Pieces in 2017, an account of more than 20 years on the front line of pol…
 
Tracy Jones Tracy Jones has over 15 years of experience working with antisocial behaviour and community safety services. She worked for Manchester City Council and Wigan Council, successfully managing teams within local authority and social housing areas, including frontline ASB services and ASB enforcement case management service. Tracy now works …
 
As the cradle of modern humanity, the African continent is home to populations with high levels of genetic diversity. But while this diversity has implications for the safety and efficacy of many drugs, African patients remain underrepresented in drug studies. In fact, while more than 400 medicines have pharmacogenetics information and public guide…
 
CSP2- Paul Walmsley Paul Walmsley, a qualified life coach, humanistic counsellor, and NLP practitioner and previously ‘Britain's Most Wanted’ criminal and spent five years on the run from the police before handing himself in in 2011. Towards the end of his ten-year prison sentence, he completed a teacher training qualification, then went on to beco…
 
CSP1 - Dr Grace Robinson Dr Grace Robinson is the Executive Director of Black Box Research and Consultancy Ltd, and a Rights Lab Research Fellow in Modern Slavery Perpetrators and Organised Crime at the University of Nottingham. She completed her Ph.D. research on Urban Street Gangs, Child Criminal Exploitation, and County Lines and regularly share…
 
In the age of evidence-based medicine, we may be tempted to dismiss intuition – the quick and automatic thought process we call “sixth sense” or “gut feeling” – as unscientific guesswork. But in clinical decision-making, intuitive reasoning is just as important as the slower and more analytical causal reasoning that healthcare professionals are tra…
 
In November 2020, longstanding UMC director Marie Lindquist began her well-earned retirement, leaving the reins of the organisation to her successor Hervé Le Louët. As she prepared to open a new chapter in her life, she sat down with Uppsala Reports to take a fond look back at an extraordinary career: a 40-year-long path that began with a knock on …
 
Medication errors with vaccines can harm individual patients, but when they also undermine trust in public health programmes, serious problems can ripple across entire communities – as the Samoan healthcare crisis of 2018 dramatically showed. The Institute for Safe Medication Practices offers straightforward advice that could prevent those errors f…
 
Clinical trials are the “gold standard” of evidence-based medicine – the best way we have to test whether a drug is safe and effective before it enters the market. But if trial data is poorly reported or – even worse – left unpublished, how are we supposed to determine the true value of a medical treatment? Peter Doshi from the RIAT Support Center …
 
Communication and public outreach are an important part of a scientist’s job. But researchers often find it daunting to translate their expert knowledge for a lay audience. In this episode, UMC’s video producer Matthew Barwick shares a report from the Global Science Film Festival 2019, including interviews with festival organiser Samer Angelone and…
 
When reporting adverse reactions to drugs, people can choose from a plethora of different terms to describe their experience. But that makes it difficult and time-consuming for analysts to tell how similar two case safety reports are. A new method developed by UMC data scientist Lucie Gattepaille comes to the rescue. This episode is part of the Upp…
 
How do we minimise the harm caused to patients by medicines and medical devices? In October 2019, a diverse, multi-stakeholder group met in Erice, Italy and drew up a 10-point plan for improving patient safety worldwide. This episode is part of the Uppsala Reports Long Reads series – the most topical stories from UMC’s pharmacovigilance magazine, b…
 
Herbal substances can be found in a number of pharmaceutical drugs, cosmetics and food supplements – so it's not surprising that using plant names inconsistently can have serious health consequences. But with so much confusion around medicinal plant names, it’s easy to get it wrong. Bob Allkin from Royal Botanic Gardens, Kew explains what we can do…
 
As the end users of medicines, patients can provide first-hand information on side effects. The issues they report add a richness to our understanding of medicine safety that we could never achieve by relying on healthcare professionals’ reports alone – so it’s crucial that we listen to them. Linda Härmark from the Netherlands pharmacovigilance cen…
 
Most of us want healthcare to be both patient-centric and evidence-based. But are those two goals compatible? Can we tailor healthcare to our unique circumstances­, while relying on the average statistical measurements that scientific evidence is based on? Emerging ideas in the philosophy of science are challenging a rigid reliance on evidence-base…
 
Most women are prescribed some form of medication during their pregnancy. Yet we know very little about the safety of those medicines when they’re used during pregnancy or breastfeeding. New collaborative efforts are now underway to plug that knowledge gap. This episode is part of the Uppsala Reports Long Reads series – the most topical stories fro…
 
Fake medicines claim at least 200,000 lives every year, with the World Health Organization estimating that 1 in 10 medicines worldwide is now substandard or falsified. But with the market in illicit drugs worth up to $200 billion a year, and traffickers more likely to face a fine than jail time when they are caught, the financial incentives far out…
 
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