Hormone Replacement, Potassium and Metabolic Disorders, Toenail Fungus | THRR066

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Potassium Intake As It Relates To Insulin Resistance, Metabolic Disorders And NAFLD; Hormone Replacement Therapy - Good? Bad?; Toenail Fungus; High BUN: Should I Be Concerned?; Where In The World To Live?

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Show Notes:

News topic du jour:

Green tea extract only affects markers of oxidative status postprandially: lasting antioxidant effect of flavonoid-free diet*

In conclusion, GTE incorporated into meat patties in doses realistic for addition to processed foods only leads to a short-term change in plasma antioxidant capacity and has no long-term effects on oxidation parameters within the blood or urine compartments in smokers or in non-smokers. The study can therefore be seen as a 10 weeks controlled study with dietary depletion of all food antioxidants derived from fruits and vegetables, except for carrots and potatoes. During the depletion we observed a decrease in oxidative damage to proteins, DNA, and lipids, concomitantly with a major reduction in plasma ascorbate and minor changes in other vitamins and in anti- oxidant enzyme activities. We speculate that these seem- ingly positive effects on oxidative status are partly due to depletion of some pro-oxidant compounds co-existing with vitamin C in fruits and vegetables and this underlines the general lack of solid knowledge of the mechanisms by which a diet rich in fruits and vegetables cause a decrease in the risk of chronic diseases.

1. Potassium intake as it relates to Insulin resistance, metabolic disorders and NAFLD [22:41]

Deirdre says: Hi Robb,

I stumbled upon a couple of journals that state there is a link between hypokalemia and IR, metabolic disorders and NAFLD, of which I have (all of them). I have a difficult time losing weight, even when following healthy eating to a T. I've been tracking my food on myfitnesspal for a month, and upon reflection, I'm not getting NEARLY enough potassium every day. Sodium doesn't seem to be an issue. I salt my food pretty well. I do magnesium soaks once or twice a week. Can you touch on this subject a bit more, and maybe make some recommendations on how to hit that 4700 mg mark for potassium daily? Even with eating a large amount of veggies and protein, it's still a difficult number to hit. Dried herbs like chervil, parsley, basil and tarragon seem to be my best bets, but it's difficult to get 100g of dried herbs in a day. LOL.

Thanks,

Deidre

1/2lb steak 800mg 1 avocado 1,000mg 1oz nuts 200mg

2. Hormone Replacement Therapy - Good? Bad? [27:22]

Marianna says: I'm a 69 YO. I'm a post menopausal female, who a little over a year ago started HRT about 18 months ago. I used bio identical HRT for the first 7 years after menopause then in keeping with recommendations went off it for about 11 years. My goal in retirement is to be as mentally and physically healthy as possible for as long as I possibly can. I'm quite active, exercise daily including cardio and strength training with yoga thrown in. Through IF and low carb eating I've recently lost 25 pounds and am5'6" and 155 lbs. The HRT I 'm using is administered via bio identical pellets every 4th month with oral progesterone taken daily. My decision to go back to HRT was prompted by reading Avrum Blooming's book Estrogen Matters. It was recently reinforced by reading Lisa Mosconi's book The XX Brain. Now finally to my question! Am I doing myself harm or good or just wasting my money (I can afford it) by seeking HRT at my age? As far as noticeable health benefits the main thing I notice is my skin looks a lot better.

Effect of menopausal hormone therapy on components of the metabolic syndrome

3. Toenail fungus [31:52]

Bradley says: Hello Robb and Nicki,

About a year ago the middle toe toenail on my left foot curled on the right side of the toe and I noticed there was fungus under the toenail. There was no pain and did not seem to be a problem. During this past summer, I went to the doctor for my regular annual blood draw and showed the doc the toenail. She said it is just cosmetic and is not an issue unless it spreads. Also, she said the only thing that can be done is take some pills, which she said is very hard on the liver, for several months until it clears, and recommended that I do not take the medication unless the fungus spreads. Then, in October/November, I noticed fungus behind the big toe toenail on my right foot. The toenail on my right foot did not curl, but, it has more of a lumpy feel and I can see the white fungus growth underneath the toenail. I still have zero pain on either foot and not sure if it is even a big concern. However, considering a conventional doctor is reluctant to put me on the medication because of the potential side effects, do you happen to know of anything else that can be done?

I have tried the foot baths with tea tree oil and other foot soaks and toenail ointments and they are not working. I have found some docs on the internet recommending special diets for around 6 months or more, but they all vary somewhat (have not attempted yet). Also, found a somewhat fringe treatment by ingesting sugar and turpentine (have not tried this either). Supposedly, the sugar attracts the parasite or fungus or whatever and the turpentine eliminates it and you just shit it all out.

Thank you both very much.

4. High BUN: should I be concerned? [39:07]

William says: Hi Robb and Nicki,

Over 5 years of taking annual bloodwork, I have found that my BUN is consistently high (30-35 mg/dL). I’ve had my own theories as to why, so see if am I on the right track with this line of thinking:

1. I’ve been a daily sauna user for the past 5 years, which could lead to dehydration and elevated urea in the blood. I drink at least a liter of water during and after, and probably an additional 1-2 L around dinner time. Total daily liquids averages 4-5L. I salt my food heavily and take Mg and K supplements, but don’t measure total electrolytes

2. I tend to eat most of my protein at night (100-150g), with a half coming in the form of plant-based protein powders

3. The blood tests are always taken first thing in the morning, so it’s possible I’m still dehydrated from the night’s of sleep, combined with the high protein intake. I don’t normally drink a lot of water upon waking because I don’t feel thirsty, although thanks to LMNT I’m starting to change that :-)

My doctor is concerned about my high BUN and an increase in chance to develop gout and kidney damage. He has advised me to reduce my protein intake. However, my avg daily protein is 150g, and as an active 165lb man, that number seems safe and appropriate. Have you looked much into BUN in people on paleo/keto diets with high protein? Are my numbers way out of whack and dangerous? Or is high BUN less of a concern in the context of a clean diet and low systemic inflammation? Could there be something else going on to contribute to this consistently high BUN? Or is it as simple is spreading my protein intake more evenly throughout the day instead of one large bolus at night? Any thoughts and insights you have would be very helpful!

Thanks!

William

5. Where In The World to Live? [44:24]

Keri says: Hi guys! Huge fan since way back in the day. Love the podcast and am grateful for all you do.

I have a weird, possibly not typical question, but value your opinions and feel like it’s relevant and something you might have an opinion on. Anyway...

My family has been working towards moving to a small, debt-free, self-sufficient farm since 2009. We’re currently ready to start looking to buy. We grew up on farms/ranches and have years of experience. We’re into regenerative agriculture, pasture raised animals etc. We also homeschool all of our kids. My question is: we can move anywhere, considering political climates, taxes, cultural/social environment, health freedoms, homeschool laws, ag environment (ie I don’t want to live right next to poison sprayed conventional fields, but need a decent growing environment) and all of the things to ponder in choosing where to live long term in this crazy world, what states would you choose?

I’m super curious if you guys have thoughts.

Strategic Relocation, North American Guide to Safe Places, Fourth Edition

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