Drs. Spencer and Karl Nadolsky talk about nutrition, medicine, and fitness through the lens of two physicians who lift weights. Both doctors are former NCAA division 1 wrestlers who have gone into medicine. Dr. Spencer Nadolsky is a board certified family physician specialized in obesity medicine and lipidology. Dr. Karl Nadolsky is a board certified endocrinologist also specialized in obesity medicine.
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Click to read Joy Prescriptions Drs. Karl and Spencer talk to Dr. Tiffany Moon all about Joy Prescriptions. Learn how to stop chasing perfection and embrace connection. 00:00Introduction to Dr. Tiffany Moon 02:02Journey to Reality TV: The Real Housewives of Dallas 05:58Life After Reality TV: Finding Joy and Purpose 09:59The Joy Prescription: A New …
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Tirzepatide is more effective for weight loss than semaglutide. Cost-effectiveness is crucial in prescribing weight loss medications. Patients with severe obesity should receive more expensive medications for better outcomes. Both medications show significant benefits for obesity-related conditions. Long-term studies indicate sustained weight loss …
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Semaglutide for metabolic dysfunction associated steatotic liver disease (MASH).
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22:20Takeaways MASH is a significant obesity-related complication. Semaglutide shows promise in treating MASH. Weight loss is crucial for improving liver health. Bariatric surgery remains the most effective treatment. The Essence trial indicates a 63% resolution of NASH. New medications are being developed for obesity treatment. Early intervention is ke…
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Drs. Karl and Spencer chat with return guest Dr. Lauren Semple about creatine, protein, cortisol, fasting exercise, and training in women. Follow Dr. Lauren's instagram Join Dr. Spencer's online clinicעל ידי Docs Who Lift
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GLP-1 and metabolism and depression
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25:00Drs. Karl and Spencer discuss a new study looking at tirzepatide and metabolic rate. They also discuss a patient case of tirzepatide induced anhedonia. Here is the tirzepatide study If interested in joining Dr. Spencer's clinic Vineyard - Click Hereעל ידי Docs Who Lift
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Do GLP-1 meds cause more fat cells?
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25:52Drs. Karl and Spencer discuss the claim that GLP-1 meds cause more fat cells. Learn about if and how GLP-1 meds increase fat cells and what that means along with other claims about these medicine. Join Dr. Spencer's online clinic that specializes in GLP-1 medicinesעל ידי Docs Who Lift
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Future of medicine - Direct Care
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23:15
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23:15Drs. Karl and Spencer talk to Dr. Kenneth Qiu all about direct medical care - the future of medicine. Learn about how bypassing insurance and creating a relationship directly with a doctor can improve your health and save money in the long run. Follow Dr. Qiu on Linked in See Dr. Spencer's direct care model with Vineyard…
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Tirzepatide and Muscle Loss with Dr. Grant Tinsley
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27:44Drs. Karl and Spencer discuss with Dr. Grant Tinsley all about the new analysis of how much "lean mass" is lost with tirzepatide, the most powerful medicine available for weight loss. Learn: The difference between fat free mass and lean mass and lean soft tissue and muscle. If GLP-1 medicines cause muscle loss specifically How to minimize muscle lo…
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Drs. Karl and Spencer discuss how bad the Hims and Hers ad was. From an outside perspective, the ad may have seemed good. But when you dig deeper, it was actually really bad. Listen to learn. Join Dr. Spencer's new online clinic - Vineyard.על ידי Docs Who Lift
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NAD and NMN with Dr. Charles Brenner
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38:56
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38:56Drs. Karl and Spencer chat with NMN and NAD expert Dr. Charles Brenner all about these supposed longevity supplements. Learn about NAD metabolism Whether it's worth supplementing or not with NAD or NMN Follow Dr. Brenner on Twitterעל ידי Docs Who Lift
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The 60 Minutes Obesity Doctor - Dr. Fatima Cody Stanford
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45:33Drs. Karl and Spencer chat with Dr. Fatima Cody Stanford all about obesity, genetics, and her appearance on 60 minutes. Does Dr. Sanford believe lifestyle doesn't matter for obesity? Find out by listening! Watch Dr. Stanford's 60 minute clip Join Dr. Spencer's Obesity Clinicעל ידי Docs Who Lift
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New Obesity Definition and Higher Wegovy Dose
29:12
29:12
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29:12Drs. Karl and Spencer chat about the new Lancet Commission's report on Clinical Obesity along with the new study on high dosed Wegovy. Learn: How 7.2 mg of Wegovy (semaglutide) compares to 2.4 mg What the proposed definitions of clinical and preclinical obesity are Click here to join Dr. Spencer's new online clinic…
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The Ozempic Revolution - with Dr. Sowa
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31:15Drs. Karl and Spencer chat with Dr. Sowa about her book The Ozempic Revolution. Learn: Why she wrote the book. The top 3 things to know when starting a GLP-1 medicine. Also hear the top criticism from Drs. Karl and Spencer. You will laugh. Click here to get the book If you're on a GLP-1 currently and want to switch to Dr. Spencer's new clinic, Clic…
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Microdosing GLP-1 and Cagrisema headlines
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40:20Drs. Karl and Spencer discuss the concept of "microdosing" GLP-1 receptor agonists along with talk about the new top line results from REDEFINE which studied the new drug CagriSema.על ידי Docs Who Lift
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Changing your workouts based on your menstrual cycle
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30:07Drs. Karl and Spencer chat with Dr. Lauren Colenso-Semple all about how the menstrual cycle and how it should affect your workout programming. Should you change your workouts around your menstrual cycle? Find out by listening! Check out her instagram Read her paper on exercise and menstrual cycles Read her paper on protein synthesis throughout the …
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Zepbound vs Wegovy trial and compounded GLP-1s
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44:15Drs. Karl and Spencer discuss the topline results from Surmount 5 which put Zepbound (tirzepatide) against Wegovy (semaglutide) for weight loss. They also discuss some news around compounded GLP-1s. Learn: Weight loss and glycemic differences between tirzepatide and semaglutide What the FDA is thinking for compounded GLP-1s If you're not on Dr. Spe…
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Types of Diabetes, CGMs, and More
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1:06:07Drs. Karl and Spencer chat with Dr. Shivani Misra, a metabolic specialist physician researcher from the UK, all about the various forms of diabetes mellitus. Learn: The types of diabetes mellitus The monogenic forms (some what refer to as MODY) The differences within type 2 diabetes Whether CGMs (continuous glucose monitors) are useful If low carb …
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A new way of delivering healthcare - Direct Primary Care
1:08:59
1:08:59
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1:08:59Drs. Karl and Spencer chat with AtlasMD - Dr. Josh Umbehr all about making healthcare cheaper using direct primary care. Learn: How cheap labs and and meds should be How cutting out the middlemen can help healthcare and decrease costs Find AtlasMD hereעל ידי Docs Who Lift
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1st longer term tirzepatide study (3 years)
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44:41
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44:41Drs. Karl and Spencer discuss the brand new 3 year study of tirzepatide in those with prediabetes along with a discussion on semaglutide treating osteoarthritis. Learn: If people lose weight and keep it off with tirzepatide How many people regain weight after stopping the medicine Long-term side effects If semaglutide helps with osteoarthritis Clic…
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Making America Healthy Again - Joe Rogan Podcast Review
53:12
53:12
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53:12Drs. Karl and Spencer invite Dr. Andrea Love back to the podcast to discuss a recent Joe Rogan podcast with Calley and Casey Means along with the concept of Make America Healthy Again and RFK jr. Learn: What the docs agree with. What they don't agree with. Is raw milk okay? Are cancer rates rising? and more Follow Dr. Andrea here https://www.instag…
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Drs. Karl and Spencer discuss all things cortisol and poke fun at the influencers who try to fear monger exercise due to cortisol increases. Learn: What is cortisol and what does it do? Is cortisol bad? Should you worry about cortisol increases with exercise? Should you take supplements to lower cortisol? and more…
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Drs. Karl and Spencer discuss their ideal healthcare delivery system. Learn: Spencer's journey building and selling Sequence and what he wants to do next. How Dr. Karl believes healthcare should be and what he's doing next. Click here to get on Dr. Spencer's waitlistעל ידי Docs Who Lift
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Obesity medicine updates and Kardashian supplements
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40:13Drs. Karl and Spencer discuss BS supplements claiming to be like Ozempic along with discuss some new obesity drugs coming down the pipeline that were announced in phase 1 and 2 trials. Are there any supplements that can mimic Ozempic? What is amylin and how does it help with weight and sugars? What is this new oral drug "amycretin" in phase 1 trial…
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Drs. Karl and Spencer chat with Dr. Jen Gunter all about menopause. Learn: How it's diagnosed. When and when not to treat. The various treatment. If it is indicated for cardiovascular disease prevention or body composition. Whether or not you should get labs. See more at Dr. Gunter's websiteעל ידי Docs Who Lift
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Olympic controversies and GLP-1 for Alzheimer's and Heart Failure
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27:26Drs. Karl and Spencer talk about the top line results from study showing liraglutide may have some benefit in Alzheimer's along with top line results from the Summit trial showing heart failure benefits with tirzepatide. They also discuss the women's boxing controversy and BMI in athletes.על ידי Docs Who Lift
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Drs. Karl and Spencer chat with return guest and bone expert endocrinologist Dr. Rachel Pessah-Pollack all about the new Vitamin D guidelines. Should healthy people even check a vitamin D level? Should they supplement with vitamin D? What people should check or supplement? Click here for the new guidelines…
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Does semaglutide cause blindness? What is NAION (nonarteritic anterio ischemic optic neuropathy)? What about worsening of diabetic retinopathy with semaglutide? What can you do to minimize the risk of NAION and retinopathy? Get the full study here Read Dr. Brugger's blogעל ידי Docs Who Lift
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Tirzepatide for Obstructive Sleep Apnea
19:37
19:37
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19:37Tirzepatide may be a good option if you have obesity and obstructive sleep apnea. Click here to read the studyעל ידי Docs Who Lift
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Stomach Ablation for Weight Loss
34:18
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34:18Click here to read about the gastric ablation and trial. Click here to see Dr. McGowan's clinicעל ידי Docs Who Lift
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Drs. Karl and Spencer discuss the recent FLOW trial where semaglutide was found to be kidney protective. They also go off about the costs of these medicines and what to do (including compounding considerations). Click here to see the studyעל ידי Docs Who Lift
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Drs. Karl and Spencer discuss the most recent South Park episode where GLP-1 medicines are discussed along with the dysfunctions of our healthcare system among other issues.על ידי Docs Who Lift
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Fallacies of Functional Medicine
26:59
26:59
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26:59Drs. Karl and Spencer discuss the fallacies of functional medicine. You'll learn what functional medicine is and whether you should seek it out.על ידי Docs Who Lift
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Another response to Jillian Michaels and Bill Maher
20:24
20:24
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20:24Drs. Karl and Spencer respond to Jillian Michaels on the Bill Maher showעל ידי Docs Who Lift
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Bariatric surgery through the mouth? Endoscopy gastroplasty 101
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38:36
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38:36Drs. Karl and Spencer discuss with gastroenterologist Dr. McGowan all about endoscopic gastroplasty. See recent study on cost effectiveness of endoscopic gastroplasty vs semaglutide Check out his programעל ידי Docs Who Lift
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GLP-1 meds and Parkinson's and Heart Failure
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24:11Drs. Karl and Spencer discuss the new studies about GLP-1 medicines and Parkinson's and heart failure along with how these meds are not just weight loss drugs but health promoting medicines. Click here to see the Parkinson's study Click here to see the heart failure studyעל ידי Docs Who Lift
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Drs. Karl and Spencer chat with Kasey Potts all about her journey with lipedema. Learn more about how this condition is diagnosed and treated. Check out her instagramעל ידי Docs Who Lift
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All about Lipedema - with Dr. Amron
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51:34
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51:34Drs. Karl and Spencer chat with Dr. Amron all about lipedema. He is a specialized surgeon who treats lipedema daily. Learn about diagnosing and treating this condition that is commonly mistaken with obesity. Check his sites https://www.dramronconsultations.com/ https://www.advancedlipedematreatment.com/…
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GLP-1 Weight Loss Maintenance from Exercise
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21:03Drs. Karl and Spencer discuss a new study showcasing the importance of exercise during and after GLP-1 medicine use. Click here to see the original study Click here to see the extension studyעל ידי Docs Who Lift
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Bustin' Hyman Myths - GLP-1 edition
28:52
28:52
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28:52Drs. Karl and Spencer discuss a recent Mark Hyman podcast where he perpetuated some myths about obesity and GLP-1 receptor agonist medicines.על ידי Docs Who Lift
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Does your doctor need to be in shape?
19:29
19:29
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19:29Drs. Karl and Spencer discuss whether your doctor needs to look a certain way in order to be a good doctor.על ידי Docs Who Lift
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Docs Who Lift and Unbiased Science Crossover
1:16:03
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1:16:03Drs. Karl and Spencer chat with Drs. Jess and Andrea all about popular podcasters like Andrew Huberman etc. and the spread of pseudoscience.על ידי Docs Who Lift
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The death of our supplement company and influencer pharma money
31:33
31:33
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31:33Drs. Karl and Spencer chat about their now defunct supplement company along with the ethics of big pharma direct to consumer marketing (including influencers).על ידי Docs Who Lift
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Drs. Karl and Spencer chat with Dr. Brianna Durand all about the pelvic floor and incontinence when lifting etc. empower.physio pelvicrehab.orgעל ידי Docs Who Lift
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How much protein should you eat? W/ Dr. Stu Phillips
44:16
44:16
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44:16Drs. Karl and Spencer chat with Dr. Stuart Phillips all about protein. How much do you need to eat for optimal health and body composition and more!על ידי Docs Who Lift
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CGMs for those without type 2 diabetes w/ Dr. Nicola Guess
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46:57Drs. Karl and Spencer chat with Dr. Nicola Guess all about the evidence behind using continuous glucose monitors in those without type 2 diabetes. Learn whether they are useful for even harmful Read her review paper hereעל ידי Docs Who Lift
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SELECT results - Wegovy reduces heart attacks
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31:22
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31:22Drs. Karl and Spencer discuss the new SELECT results that show a decrease in cardiovascular events in those taking Wegovy who have a history of cardiovascular disease. See trial below https://www.nejm.org/doi/full/10.1056/NEJMoa2307563על ידי Docs Who Lift
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Zepbound - Tirzepatide for obesity approval
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23:05
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23:05Drs. Karl and Spencer discuss how tirzepatide is now approved for obesity. Learn: When will it be available How much will is cost Any differences compared to Mounjaro Surmount 3 trialעל ידי Docs Who Lift
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Drs. Karl and Spencer chat with Dr. Kathleen Keller and Yash Adroja all about brain signaling in kids in relation to obesity. Learn all about Dr. Keller's research that sheds light on taste preferences and food choices made by kids.על ידי Docs Who Lift
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Drs. Karl and Spencer chat about some of the new tirzepatide studies including SURMOUNT-4 from the EASDעל ידי Docs Who Lift
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Drs. Karl and Spencer discuss with Dr. Bassin all about her review on exercise and physical activity for type 2 diabetes. Check out her review articleעל ידי Docs Who Lift
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