Concise summaries of everything published in the latest weekly issue of the New England Journal of Medicine (NEJM). NEJM publishes new medical research findings, review articles, and editorial opinion on topics of importance to biomedical science and clinical practice.
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NEJM AI Grand Rounds, hosted by Arjun (Raj) Manrai, Ph.D. and Andrew Beam, Ph.D., features informal conversations with a variety of unique experts exploring the deep issues at the intersection of artificial intelligence, machine learning, and medicine. You’ll learn how AI will change clinical practice and healthcare, how it will impact the patient experience, and about the people who are pushing for innovation. Whether you are an AI researcher or a practicing clinician, these conversations w ...
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Insightful conversations with leading experts in the field of health care, medical research, policy, and more from the New England Journal of Medicine (NEJM). Each episode examines the many complexities found at the junction of medicine and society.
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Audio podcasts featuring the week’s top medical news plus pertinent interviews
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The House reflects medicine’s most pressing issues through the eyes of residents, providing a forum to share their stories from the bedside, where they are learning far more than the lessons of clinical medicine.
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A Day in the Life is a podcast for medical students, by medical students. Interviews with attendings about daily life and training may help you explore a range of specialties.
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NEJM Interview: Lauren Schiff on the need for improved training and increased comfort in treating autistic people.
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Lauren Schiff is an associate professor of Ob/Gyn and a minimally invasive gynecologic surgeon at the University of North Carolina School of Medicine and the associate chief medical officer for quality and safety at UNC Hospitals. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. L.D. Schiff, A.O.D. Hester, and T.…
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NEJM This Week — December 19, 2024
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Featuring articles on cancer cachexia, MDR tuberculosis, Ebola virus disease, and severe asthma; a review article on the nonsurgical management of chronic venous insufficiency; a case report of a woman with end-stage liver disease and headache; and Perspectives on providing effective medical care to autistic people, on independent physician associa…
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The Economics of AI: A Conversation with Larry Summers
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In this episode of NEJM AI Grand Rounds, hosts Raj Manrai and Andy Beam interview Larry Summers about artificial intelligence’s transformative potential and its implications for society. The conversation explores Summers’ perspective on AI as potentially the most significant technology ever invented, his role on OpenAI’s board following the Novembe…
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NEJM Interview: Bindu Kanapuru on the FDA’s new expedited withdrawal procedure for accelerated approvals.
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Bindu Kanapuru is a hematologist–oncologist physician in the Office of Oncologic Diseases at the FDA’s Center for Drug Evaluation and Research. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. B. Kanapuru and Others. Autopsy of a Drug Withdrawal — The Case of Melphalan Flufenamide. N Engl J Med 2024;391:2177-2179…
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NEJM This Week — December 12, 2024
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Featuring articles on PCI before transcatheter aortic-valve implantation, treatments in patients with type 2 diabetes, in leprosy, in refractory adult ALL, and in ATTR cardiomyopathy; a review article on drug reaction with eosinophilia and systemic symptoms; a case report of a boy with recurrent fever; and Perspectives on an autopsy of a drug withd…
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NEJM Interview: Karen Joynt Maddox on the Transforming Episode Accountability Model recently announced by CMS.
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Karen Joynt Maddox is an associate professor of medicine at Washington University School of Medicine. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. S.A. Shashikumar, A.M. Ryan, and K.E. Joynt Maddox. Medicare’s New Mandatory Bundled-Payment Program — Are We Ready for TEAM? N Engl J Med 2024;391:2065-2067.…
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NEJM This Week — December 5, 2024
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Featuring articles on treatments for atrial fibrillation and stable coronary disease, for chronic hepatitis B, and for metastatic breast cancer; the 30-year cardiovascular disease risk in healthy women; and prenatal screening and detection of maternal cancer; a review article on sepsis and septic shock; a case report of a woman with headache, fever…
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NEJM Interview: Andrew Hantel on a source of discrimination against some patients in cancer research and care practices.
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Andrew Hantel is an assistant professor of medicine at Harvard Medical School and a faculty member in the Divisions of Leukemia and Population Sciences at Dana-Farber Cancer Institute and at the HMS Center for Bioethics. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. A. Hantel and Others. The Duffy Null Phenoty…
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NEJM This Week — November 28, 2024
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Featuring articles on pembrolizumab perioperative therapy in breast cancer, reduced dose schedules or fractional doses of pneumococcal conjugate vaccine, and nivolumab plus ipilimumab in colorectal cancer; a review article on degenerative rotator-cuff disorders; a case report of a man with seizures and agitation; a Clinical Implications of Basic Re…
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NEJM Interview: Benjamin Rome on the results of the initial round of drug-price negotiation under the Inflation Reduction Act.
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Benjamin Rome is a physician and health policy researcher at Brigham and Women’s Hospital and an assistant professor of medicine at Harvard Medical School. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. B.N. Rome, A.S. Kesselheim, and W.B. Feldman. Medicare’s First Round of Drug-Price Negotiation — Measuring Su…
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NEJM This Week — November 21, 2024
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Featuring articles on a nationwide couple-based genetic screening; adjunctive embolization for subdural hematoma; a late-liver-stage attenuated malaria vaccine; and climate change, floods, and human health; a review article on Candida auris infections; a case report of a girl with abdominal pain; and Perspectives on Medicare’s first round of drug-p…
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Partners in Diagnosis: ChatGPT, a Mother’s Intuition, and a Doctor’s Expertise with Courtney Hofmann and Dr. Holly Gilmer
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In this episode of NEJM AI Grand Rounds, hosts Raj Manrai and Andy Beam interview Courtney Hofmann, a mother whose use of ChatGPT led to her son’s diagnosis of tethered cord syndrome after seeing 17 doctors over three years, and Dr. Holly Gilmer, the pediatric neurosurgeon who confirmed and treated the condition. The conversation explores how AI he…
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NEJM at AHA — Phase 1 Study of AAV9.LAMP2B Gene Therapy in Danon Disease
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Eric Rubin is the Editor-in-Chief of the Journal. Jane Leopold is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, J. Leopold, and S. Morrissey. NEJM at AHA — Phase 1 Study of AAV9.LAMP2B Gene Therapy in Danon Disease. N Engl J Med. DOI: 10.1056/NEJMe2414477.…
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NEJM at AHA — Routine Spironolactone in Acute Myocardial Infarction
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Eric Rubin is the Editor-in-Chief of the Journal. Jane Leopold is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, J. Leopold, and S. Morrissey. NEJM at AHA — Routine Spironolactone in Acute Myocardial Infarction. N Engl J Med. DOI: 10.1056/NEJMe2414472.…
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NEJM at AHA — Catheter Ablation or Antiarrhythmic Drugs for Ventricular Tachycardia
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Eric Rubin is the Editor-in-Chief of the Journal. Jane Leopold is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, J. Leopold, and S. Morrissey. NEJM at AHA — Catheter Ablation or Antiarrhythmic Drugs for Ventricular Tachycardia. N Engl J Med. DOI: 10.1056/NEJMe2414471.…
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NEJM at AHA — CRISPR-Cas9 Gene Editing with Nexiguran Ziclumeran for ATTR Cardiomyopathy
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Eric Rubin is the Editor-in-Chief of the Journal. Jane Leopold is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, J. Leopold, and S. Morrissey. NEJM at AHA — CRISPR-Cas9 Gene Editing with Nexiguran Ziclumeran for ATTR Cardiomyopathy. N Engl J Med. DOI: 10.1056/NEJMe241…
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NEJM at AHA — Left Atrial Appendage Closure after Ablation for Atrial Fibrillation
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Eric Rubin is the Editor-in-Chief of the Journal. Jane Leopold is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, J. Leopold, and S. Morrissey. NEJM at AHA — Left Atrial Appendage Closure after Ablation for Atrial Fibrillation. N Engl J Med. DOI: 10.1056/NEJMe2414475.…
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NEJM at AHA — Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity
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Eric Rubin is the Editor-in-Chief of the Journal. Jane Leopold is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, J. Leopold, and S. Morrissey. NEJM at AHA — Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity. N Engl J Med. DOI: 10.1056/NEJMe241…
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NEJM at AHA — Intensive Blood-Pressure Control in Patients with Type 2 Diabetes
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Eric Rubin is the Editor-in-Chief of the Journal. Jane Leopold is a Deputy Editor of the Journal. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin, J. Leopold, and S. Morrissey. NEJM at AHA — Intensive Blood-Pressure Control in Patients with Type 2 Diabetes. N Engl J Med. DOI: 10.1056/NEJMe2414476.…
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NEJM Interview: Heather Hsu on an institutional conference series that provides opportunities for addressing the adverse effects of bias and medical racism.
8:27
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Heather Hsu is a pediatric hospitalist at Boston Medical Center and an assistant professor of pediatrics at the Boston University Chobanian and Avedisian School of Medicine. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. K.A. Nash, J. Perdomo, and H.E. Hsu. Health Equity Rounds — Root-Cause and Solutions-Orient…
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NEJM This Week — November 14, 2024
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Featuring articles on perioperative durvalumab in bladder cancer, transcatheter valve repair for mitral regurgitation, chemoradiotherapy in gastric cancer, and lessons from England’s National Health Service; a review article on lung transplantation; a case report of a newborn with hypoxemia and a lung opacity; and Perspectives on our latest brief c…
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The Marburg Virus Outbreak in Rwanda
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Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Sabin Nsanzimana, M.D., Ph.D., is the Minister of Health of Rwanda. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.J. Rubin and Others. Audio Interview: The Marburg Virus Outbreak in Rwanda. N Engl J Med 2024;39…
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NEJM Interview: Vincent Guilamo-Ramos on the need to rethink the response to HIV in Latino communities.
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Vincent Guilamo-Ramos is the executive director of the Institute for Policy Solutions at the Johns Hopkins School of Nursing. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. V. Guilamo-Ramos, M. Thimm-Kaiser, and A. Benzekri. The U.S. Latino HIV Crisis — Ending an Era of Invisibility. N Engl J Med 2024;391:1665-…
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NEJM This Week — November 7, 2024
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Featuring articles on an invasive treatment strategy in older patients with myocardial infarction, a randomized trial of very early medication abortion, therapies in stage III melanoma, and on long Covid defined; a review article on uterine fibroids; a Clinical Problem-Solving on two sides to the story; and Perspectives on the U.S. Latino HIV crisi…
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NEJM Interview: Liam McCoy on concerns about the implementation of large language models in note writing and related clinical tasks.
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Liam McCoy is a resident physician in neurology at the University of Alberta. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. L.G. McCoy, A.K. Manrai, and A. Rodman. Large Language Models and the Degradation of the Medical Record. N Engl J Med 2024;391:1561-1564.
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NEJM This Week — October 31, 2024
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Featuring articles on semaglutide in persons with obesity and knee osteoarthritis, the addition of PI3K inhibition in breast cancer, treatments in older patients with myeloma, and total hip replacement for hip osteoarthritis; a review article on lead poisoning; a case report of a man with dyspnea after old myocardial infarction; and Perspectives on…
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