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The data revolution has begun. The knowledge you will gain over your body, your health, your performance, will explode in the next 5 years. Empowering you to make better decisions about your body and get the results you’re looking for, instead of just guessing or following the latest opinion fad in health or fitness or anti-aging. The Quantified Body introduces you to the cutting edge in this trend – wearable devices, biomarkers, the latest lab tests, quantified self protocols, biohacking ta ...
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Rejuvenation biotech is a new industry forming around the theme of life extension technologies. This episode provides a broad look at the state of the industry, its most promising life extension technologies and their potential timelines. Life extension - this is something I've wanted to spend time on for a while. In this episode, I interview 5 tho…
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Microbiome testing can be confusing: many companies, different technologies and a lack of standards make it hard to get actionable insights from the data. Find out how technologies and labs differ and what information is actionable from today's microbiome tests. In this episode we continue our discussion of the microbiome that we started in Episode…
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What is carbohydrate intolerance? Do each of us have a personal tolerance or intolerance of carbohydrates? Does this also vary by source of carbohydrate? Learn how evolutionary tools may explain appetite regulation and carbohydrate metabolism and offer ways to regain carb tolerance through diet and lifestyle modifications. In this episode, we explo…
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Is your glucose metabolism driven by your personal microbiome? Recent research reveals how the microbiome influences blood glucose, weight gain and weight loss. And how the new company, "Day Two", is using microbiome sequencing data to provide personalized nutrition recommendations. In this episode we discuss how personal your blood glucose respons…
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Recent investigations have shown supplements to not always contain what they say they do. Or at other times to have unwanted contaminants such as heavy metals. Learn to use 3rd party lab testing to select supplements that contain the active ingredients needed to provide the results you seek. Sometimes on this show, we discuss using supplements as t…
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Micronutrient status is a foundation of health, performance and chronic disease minimization. This episode looks at how to optimize fat soluble micronutrients status. In this episode we look at ensuring micronutrient status. Ensuring your body has the building blocks it needs to do what it needs to do. This is an important lever to increasing your …
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Ketone bodies, whether gained from fasting, keto diets, MCTs or exogenous ketones have many potential applications with benefits ranging from performance, to health, to longevity and mitigating symptoms and risks of certain diseases. There is growing evidence that ketone bodies, whether they come from fasting, keto diets, MCTs or exogenous ketones …
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Putting the body into ketosis and controlling blood glucose levels may prove to be effective therapy against certain cancers. This real case reveals one aggressive self-experimenter who used a combination of the ketogenic diet, fasting and other tools to control his epilepsy and send his brain cancer into remission. This episode examines the ketoge…
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43: Learnings from Continuous Glucose Monitoring (and the Future of Blood Sugar Management Tech) – Tim Omer
Most of us have non-optimal blood glucose regulation today.The impact? Reduced performance, and reduced longevity. We wrongly assume that it's only diabetics that are exposed to these issues. This episode explores using continuous glucose monitoring and other tech to optimize blood sugar through the eyes of a diabetic self-experimenter. How can blo…
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Part 3 in our series of Fasting Self-Experiments. In this longer 10 day water fast I tracked results with a broad set of biomarkers (ketones, glucose, weight, hormones and cognitive performance panels). This is a long post - if that scares you, jump directly to what you're looking for: Why Do a 10 Day Water Fast? (The health benefits that we're opt…
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A look at how to accurately quantify your cardiovascular fitness in order to optimize endurance sports or your cardiovascular health. Is VO2Max the gold standard? Are the metrics in the current "fitness trackers" useful for this goal? In this episode we look at different ways to track fitness. Previously we have talked about VO2 max and Heart Rate …
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Heart disease affects 50% of the U.S. population in their lifetime. Learn how to accurately quantify your personal heart disease status and risk, and if necessary, take clear actions to reduce that risk by eliminating plaque in the arteries. This episode presents an in depth look at heart disease because this is one of the most likely things to sho…
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Meditation - ever more popular as studies pile up proving its benefits. However, how do you assure yourself that you gain the same benefits with your meditation practice? Muse Calm is a neurofeedback device that promises accurate feedback on the quality of your meditation. In this episode we talk about improving your focus and meditation practice w…
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What is genetic testing able to do and not do with current services? We talk with one of the top genetic lab services to understand how technologies differ in accuracy and where it is working, where it is not yet ready and why. In this episode we look at the impact that genetics has on our health and wellness. With rapid discoveries in epigenetics,…
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What defines human microbiome health? The co-founder of American Gut Project discusses the differences we've found in the gut microbiome and how it influences our health. We look at tools and lifestyle choices that have been shown to change the microbiome (for good, and for bad). Our microbiome plays an important role in our ability to overcome hea…
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Water fasting or ketogenic therapies may be effective with some cancers, and not with others. Learn about the PET scan and how it can provide insights into whether a cancer is likely to be responsive or not to the water fast tactic we've covered in previous episodes. In this episode, we return to look at ketosis and water fasts as a tool to help tr…
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An in-depth look at using heart rate variability biofeedback with slow breathing to reduce stress, enhance athletic performance and provide therapeutic support for some chronic health issues. Heart rate variability biofeedback is being used primarily to reset the nervous system and thus as an antidote to different types of stressors. These include …
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A look at a collection of high impact endurance tools and tactics - and the top biomarkers to watch for optimization. Vetted by an endurance athlete with years of experiments and competitions behind him. Today's episode is about endurance training and using high-impact tools to get the most out of it. We look at self-tracking in diet and exercise w…
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33: How to Know What Improves Your Mental Performance (in Only a Few Minutes per Day) – Yoni Donner
We strive for the best mental performance but how do you know if your routines (sleep patterns, coffee habits, etc.) are helping or hurting? The Quantified Mind is a web-based project that allows you to quickly check your cognitive function in a few minutes. In previous episodes, we have discussed and identified ways to improve our mental performan…
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32: Quantified Medicine: Working with a Quant-Friendly Physician and Where Self-Tracking Makes Medicine Better – Paul Abramson
Can physicians improve health outcomes using new self-tracking tech with their patients? Or is the tech still too inaccurate or impractical? We take a hard look at the reality and potential with a physician testing quantified self practices in his clinic for the last 3 years. This episode is about quantified medicine or the reality of cooperating w…
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Oxaloacetate is an important metabolic intermediate in the energy pathway of the mitochondria. Recent case studies support the use of oxaloacetate as a nutritional supplement to help regulate blood glucose levels, potentially support longevity and protect the brain. Can you get similar beneficial results from a nutritional supplement as you can fro…
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Mitochondria, the power plants of our body, get damaged through aging and other stressors. Lipid Replacement Therapy (LRT) is a tool being used to repair part of this damage to mitochondrial membranes, and can help people recover and optimize their energy levels. The mitochondria is often described as the "powerhouse" of the cell and it supplies th…
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A walk-through of the 5-day water fast with the tracked results (ketones, glucose, weight) and the practical do's and don'ts to make the most of the experience. I'm not a fan of cancer. The only people I've lost in memory - my grandfather and other close family - it was cancer that took them. NOT putting an end to the fun of life because of cancer …
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Have you been using Dual-N-Back or other braining tools? A look at failed brain training experiments and how to assess real mental performance improvement with Dr. Adrian Owen. In today's fast paced, technologically advanced world strong mental performance is of utmost importance. From our abilities in the work place to our interactions in social s…
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How well are you aging? We look at an attempt to make an aging biomarker index accessible to consumers that tracks their true biological age and provides feedback recommendations to improve how they age. In this episode we take another look at longevity through the lens of aging biomarkers. This time taking a look at some of the most well research-…
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What is the best biomarker to track your oxidative stress burden? Joshua Fessel explains why F2-isoprostanes provide the best assessment of our ongoing oxidative state. Today's topic is understanding your oxidative stress levels via lipid peroxidation. We previously took a broad look at measuring and lowering oxidative stress in episode 4 with Dr. …
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This episode is about experimenters in the field of biohacking, the people actually in the trenches doing stuff. We’re focusing on wearable devices such as watches, shirts, bracelets, necklaces and on and on. We're focusing on wearable devices such as watches, shirts, bracelets, necklaces and on an on. Basically, anything that you can put on your b…
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Today we return to the topic of detoxification. A simple and universal lever everyone can use in the quest for better health, detoxification is a worthwhile endeavor whether you suffer from a chronic disease or are an athlete seeking to gain a performance edge. Previously on The Quantified Body, we looked specifically at toxicity issues surrounding…
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22: Bob Troia: N=1 Experiments (Bulletproof Diet, Intermittent Fasting, Blood Glucose Regulation and More)
Today's episode is about practical tools that we can use to improve our biology and how we can track those results to make sure we are getting the right answers. This episode can serve as an important source of information about N=1 experiments and biohacking. N=1 experiments involve a single subject and they are entirely capable of providing stati…
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Recently, transcranial direct current stimulation (tDCS) or the non-invasive targeting of weak direct current (DC) to specific brain regions has received media attention. Among the scientific research community, tDCS has been a subject of great interest owing to its usage ease, relative inexpensiveness, and encouraging research results on a range o…
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Is Heart Rate Variability the best biomarker of the time to track our longevity? In this episode we look at why HRV may be the best way to track how well you are aging and the bets being placed on it in Silicon Valley to drive innovation in anti-aging and longevity research. Previously we've looked at using HRV for training and recovery, stress man…
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Today our bodies, particularly our bones, are burdened with one to two thousands times the level of lead that our ancestors carried. As recently as seven hundred years ago (prior to the industrialized age) human skeletal remains contained very low levels of lead. Once the earth’s crust was disturbed through mining, much higher levels of lead were r…
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According to a 2015 consumer wearables report, 1 in 10 Americans has a fitness tracker. Yet there have been various media reports questioning the accuracy of these devices. Today we talk about whether the accuracy of fitness trackers matters; upcoming research trends; and, the most important question, even if they are accurate, are fitness trackers…
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Micro-nutrient deficiencies are prevalent today, and prevent our biology from functioning optimally by limiting its activity. The most common and most severe micro-nutrient deficiency for most of us is Magnesium. A hundred years ago we were able to get five hundred milligrams per day of Magnesium. Today we get closer to two hundred milligrams per d…
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Is some aspect of mitochondrial damage behind cancer? If so, can this theory help us take control of cancer via tactics such as yearly or more frequent "7 day water fasts". When we think about death, cancer is often what we think of first. If you're like me, most, if not all, of the deaths affecting you personally in your life may have been due to …
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This week’s podcast is about the rising movement for quantifying our lives beyond just health and body. The Quantified Self is about self-knowledge through self-tracking and extends our awareness about what’s happening in our lives, how we’re spending our time, and pretty much anything related to our daily living. In 2007 Ernesto Ramirez joined wit…
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A walk-through of a practical framework designed to achieve what most of us believe is impossible - completely eliminate aging. Learn about the 7 ways we age, and how scientists are trying to design tools to repair each one of them. Today is our first episode on aging. Longevity is a subject close to my heart, and I’ve been following the career of …
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Toxins negatively impact our health, longevity and performance in a variety of ways. Today we look at one of the most important toxins all of us are exposed to in today’s environment - mercury. It finds its way into our bodies in many ways: through our dental amalgams, the fish we eat, and vaccines, to name a few. Essentially, we are looking at qua…
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12: Jeffrey Bland PhD: Assessing the Body via the Functional Medicine Framework and Your Detoxification System
Functional medicine is a framework for tackling health issues and an approach to optimizing health that contrasts sharply with today's "standard of care" medicine model. In this episode we look at assessing the body via the functional medicine framework and your detoxification system. Where "standard of care" excels at dealing with acute health cri…
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Today we're looking at HRV- endurance training, adrenal fatigue, and future app developments. If you didn't listen to it, in Episode 1 we primarily looked at resistance training, or weight training. Today we also look at some scenarios where the HRV metric can be confounded where an increase in it is not good, how it can be used to identify possibl…
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A different philosophy: Leverage highly time efficient workouts to increase strength, build lean mass, promote cardiovascular performance and provide longevity benefits. In 2009 I found my time getting swallowed up by the demands of my career job while starting my own business on the side and trying to keep to my crossfit workout program (which I d…
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A couple of cutting edge and very relevant quantified body topics today- quantifying the microbiome and the state of crowd science We’re looking at the microbiome, which you probably have seen is the big new topic in the health media and news the last few years. Research is increasingly relating differences in our microbiomes to a range of disease …
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What is it that makes our bodies stronger? Gives them greater longevity? Greater resilience to disease? Greater performance? The strange answer to this is that often something that harms us, stresses us, is what ends up making us stronger. The process is known as "hormesis" and applies to pretty much everything we can think of. Low doses of all typ…
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In the first episode of The Quantified Body, we looked at the biometric of Heart Rate Variability or HRV and how to apply it to optimize training and workouts. HRV has also been researched in other contexts such as stress management, general health, motivation, and willpower, where it can help you make decisions about how to improve these areas and…
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Today's episode takes a look at Methylation, it's role and importance for many body functions, how it can enhance our quality of life and performance when running properly, or expose us to greater health risks like heart disease or cancer when it doesn’t. Addressing methylation SNPs (genetic mutations that we all have some of to varying degrees) an…
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The paradox: We spend a lot of money and time on increasing our antioxidant intake through foods and supplements. Yet most of us never know if this effort is making any impact on our health. Should we be checking our oxidative stress levels as often as we check our cholesterol? Not a day goes past that we don't hear about oxidative stress in the ne…
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Are your autoimmune and chronic health issues driven by mitochondrial damage? Could nutritional and other simple approaches targeting improved mitochondrial function provide the answer to many of our modern day ailments? When we think about health risk, and reducing it, most of us are thinking about cancer, heart disease and strokes. Autoimmune and…
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Our performance and quality of life is largely dependent on a delicate balance of brain biochemistry. It defines our mental health, mood, our anxiety, our focus and attention, cognitive performance and ultimately even our personality. Today's guest estimates that 80 to 90% of the population have some kind of biochemistry abnormality that affects th…
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Whether you’re a professional athlete or a weekend warrior, taking a break from mental work to hit the gym at weekends, recovery is an important part of how you train. When we don’t recover sufficiently we end up decreasing our performance and health rather than getting the results we desire - higher performance, beating our records and increasing …
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