Dr. Brendan McCarthy podcast

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הוסף לפני three שנים

תוכן מסופק על ידי Dr. Brendan McCarthy. כל תוכן הפודקאסטים כולל פרקים, גרפיקה ותיאורי פודקאסטים מועלים ומסופקים ישירות על ידי Dr. Brendan McCarthy או שותף פלטפורמת הפודקאסט שלהם. אם אתה מאמין שמישהו משתמש ביצירה שלך המוגנת בזכויות יוצרים ללא רשותך, אתה יכול לעקוב אחר התהליך המתואר כאן https://he.player.fm/legal.

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(#1) Elise’s Top Ten: The psychology of your future self | Dan Gilbert 9:24

לפני 11 weeks9:24

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9:24

"Human beings are works in progress that mistakenly think they're finished." Dan Gilbert shares recent research on a phenomenon he calls the "end of history illusion," where we somehow imagine that the person we are right now is the person we'll be for the rest of time. Hint: that's not the case. Hosted on Acast. See acast.com/privacy for more information.…

Dr. Brendan McCarthy

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Welcome! Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. Through successful case after successful case, Dr. McCarthy has been dedicated to hormone balance, healthy metabolism, and the best quality of life. Dr. McCarthy’s hallmark is his unorthodox approach to mental/emotional wellness and its link to hormone balance in women and men. Through the use of blood work and clinical investigation, Dr. McCarthy gets to the bottom of possible causes for common conditions such as anxiety, PMS, depression, slow metabolism, weight gain, insomnia and now wants to share his knowledge to the viewers with his podcast. Join the discussion, ask questions, and welcome to the podcast!

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#Science #Fitness #Alternative Health #Podcasting Education #Dr Brendan McCarthy #Brendan McCarthy

Dr. Brendan McCarthy

updated לפני 21 שעות

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164 פרקים

#Science #Fitness #Alternative Health #Podcasting Education #Dr Brendan McCarthy #Brendan McCarthy

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Dr. Brendan McCarthy

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Progesterone: The Breakthrough Women Deserve 26:46

לפני 21 hours26:46

26:46

In today’s episode, I’m opening the first chapter of what I believe is the most important series I’ve ever created — a deep dive into progesterone and why it became the heart of my medical practice. For more than 20 years, I’ve watched this “simple, humble hormone” transform women’s lives in ways most conventional medicine overlooks. What started in two small treatment rooms has grown into a 25,000 sq ft facility, and the core of our success comes down to understanding progesterone’s impact on the female brain, stress response, and emotional resilience. In this episode, I break down: Why progesterone is far more than a reproductive hormone How it regulates the female stress response (amygdala, hippocampus, prefrontal cortex) Why anxiety, insomnia, irritability, and emotional overwhelm often map directly to progesterone decline Why so many women feel “unraveled” in their 40s — and why it’s not their fault The science behind oral vs. sublingual progesterone (and why I use troches) How conventional medicine often misses the root cause The importance of physicians showing their work, their data, and their citations The lived stories and clinical outcomes that changed how I practice medicine If you’ve ever felt dismissed, unseen, or told that your anxiety or mood changes are “just stress,” this episode is for you. This is the beginning of a 7-part series where I break down the neurobiology, endocrinology, testing, dosing, delivery methods, breast health, perimenopause, and more. Citations: Brinton, Roberta Diaz, et al. “Neurosteroids and Brain Function.” Steroids, vol. 81, 2014, pp. 61–78. Epperson, C. Neill, et al. “New Insights into Perimenopausal Depression: A Neuroendocrine Vulnerability Framework.” The Lancet Psychiatry, vol. 9, no. 2, 2022, pp. 110–118. Frye, Cheryl A. “Neurosteroids—Endogenous Modulators of GABA_A Receptors.” Pharmacology & Therapeutics, vol. 116, no. 1, 2007, pp. 58–76. Genazzani, Andrea R., et al. “Progesterone, Stress, and the Brain.” Human Reproduction Update, vol. 16, no. 6, 2010, pp. 641–655. Meeker, John D., et al. “Environmental Endocrine Disruptors: Their Effects on Human Reproduction and Development.” Reproductive Toxicology, vol. 25, 2008, pp. 1–7. Mellon, Stanley H. “Neurosteroid Regulation of Central Nervous System Development.” Pharmacology & Therapeutics, vol. 116, 2007, pp. 107–124. Mizrahi, Romy, et al. “The Role of Allopregnanolone in Stress, Mood, and Trauma.” Neurobiology of Stress, vol. 11, 2019, 100198. Paul, Steven M., and Graziano Pinna. “Allopregnanolone: From Molecular Pathways to Therapeutic Applications.” Current Opinion in Neurobiology, vol. 48, 2018, pp. 90–96. Pluchino, Nicoletta, et al. “Progesterone and Allopregnanolone: Effects on the Central Nervous System in the Luteal Phase and in Perimenopause.” Gynecological Endocrinology, vol. 36, no. 6, 2020, pp. 441–445. Rasgon, Natalie L., et al. “Perimenopausal Changes in the Brain and Mood: A Review.” Journal of Clinical Endocrinology and Metabolism, vol. 107, no. 4, 2022, pp. 1120–1134. Reddy, Doodipala Samba. “The Neurosteroid Allopregnanolone and GABA-A Receptor Modulation in Epilepsy and Mood Disorders.” Frontiers in Neuroscience, vol. 12, 2018, 933. Schiller, Crystal E., et al. “The Neuroendocrinology of Perimenopausal Depression.” Trends in Neurosciences, vol. 44, no. 2, 2021, pp. 119–135. Schumacher, Michael, et al. “Neuroprotective Effects of Progesterone and Its Metabolites.” Frontiers in Neuroendocrinology, vol. 33, 2012, pp. 415–439. Selye, Hans. “The General Adaptation Syndrome and the Diseases of Adaptation.” Journal of Clinical Endocrinology, vol. 6, no. 2, 1946, pp. 117–230. Sheng, Jun, and György Buzsáki. “Neuronal Firing and Theta Oscillations in the Amygdala During Fear Conditioning.” Neuron, vol. 53, 2007, pp. 653–667. Smith, Sheryl S. “Progesterone Withdrawal Increases Neuronal Excitability in the Hippocampus: A GABA_A Mechanism.” Journal of Neuroscience, vol. 28, 2008, pp. 10171–10179. Snyder, Jonathan S., et al. “Adult Hippocampal Neurogenesis and Stress Regulation.” Nature Reviews Neuroscience, vol. 12, 2011, pp. 1–9. Stanczyk, Frank Z., and Jerilynn C. Prior. “Progesterone and Progestins: A Review of Pharmacology, PK, and Clinical Use.” Steroids, vol. 82, 2014, pp. 1–8. Tu, Ming-Je, et al. “Oral, Vaginal, and Transdermal Progesterone: PK, Metabolism, and Tissue Distribution.” Drug Metabolism Reviews, vol. 52, no. 2, 2020, pp. 1–28. Wang, Jun, et al. “Stress, Amygdala Plasticity, and the Neuroendocrine Interface.” Nature Neuroscience, vol. 10, 2007, pp. 1093–1100. Weinstock, Marta. “The Hippocampus and Chronic Stress.” Neurochemical Research, vol. 42, 2017, pp. 1–12. World Health Organization. Progesterone and Reproductive Function: Clinical Perspectives. WHO, 2019. Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he’s helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He’s also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you’re ready to take your health seriously, this podcast is a great place to start. 👇 Tap Subscribe to learn more about what’s actually happening in your body, and what to do about it. 📘 Read Dr. McCarthy’s Book: Jump Off the Mood Swing – A Sane Woman’s Guide to Her Crazy Hormones https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 📲 Follow Dr. McCarthy: Instagram: @drbrendanmccarthy TikTok: @drbrendanmccarthy Website: www.protealife.com 💬 Got a question or topic for a future episode? Let us know in the comments!…

Dr. Brendan McCarthy

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The Truth About Estrone: What Your Lab Work Isn’t Telling You 43:37

לפני 8 ימים43:37

43:37

Join Dr. Brendan McCarthy, Chief Medical Officer at Protea Medical Center in Tempe, Arizona, for a deep, practical breakdown of estrone—one of the most misunderstood and under-tested hormones in women’s health. In this episode, Dr. McCarthy explains: Why estrone matters far more than most routine labs suggest How estrone relates to inflammation, insulin resistance, body fat, and chronic disease What your estrone actually tells you about your metabolic load How phase 1 and phase 2 liver detox pathways determine whether estrogen becomes helpful or harmful How to use food, supplements, and prescriptions appropriately based on your labs Red flags to watch for with boutique labs, overpriced clinics, and “hormone hacks” You’ll learn exactly how clinicians should evaluate estrone, how to interpret the estrone–estradiol ratio, and how to identify where estrogen metabolism is blocked so you can take meaningful steps toward better health. If you find this helpful, please subscribe and share it with someone who wants real, evidence-based hormone education. Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he’s helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He’s also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you’re ready to take your health seriously, this podcast is a great place to start. 👇 Tap Subscribe to learn more about what’s actually happening in your body, and what to do about it. 📘 Read Dr. McCarthy’s Book: Jump Off the Mood Swing – A Sane Woman’s Guide to Her Crazy Hormones https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 📲 Follow Dr. McCarthy: Instagram: @drbrendanmccarthy TikTok: @drbrendanmccarthy Website: www.protealife.com 💬 Got a question or topic for a future episode? Let us know in the comments!…

Dr. Brendan McCarthy

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The Estrone Pathways That Predict Your Health: Labs Your Doctor Isn’t Running 31:00

לפני 15 ימים31:00

31:00

In this episode, Dr. Brendan McCarthy, Chief Medical Officer at Protea Medical Center in Tempe, Arizona, takes you deep into the science of Estrone metabolism, why it becomes dominant during perimenopause and menopause, and the exact lab tests that uncover real root causes of symptoms like weight gain, mood swings, breast tenderness, irritability, fatigue, and sleep disruption. This is Part 4 of our Estrone Series — and today’s focus is the real, science-based pathways behind estrone dominance: Estrone : Estradiol ratios 2-, 4-, and 16-hydroxyestrone pathways COMT function and methylation Liver health and detoxification capacity The nutrients and lifestyle factors that shift estrogen metabolism How to interpret patterns your regular doctor may overlook If you’ve ever been dismissed, told your symptoms are “normal,” or felt like something is wrong that no one is addressing — this episode gives you the tools, the labs, and the language to advocate for your health. Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he’s helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He’s also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you’re ready to take your health seriously, this podcast is a great place to start. 👇 Tap Subscribe to learn more about what’s actually happening in your body, and what to do about it. 📘 Read Dr. McCarthy’s Book: Jump Off the Mood Swing – A Sane Woman’s Guide to Her Crazy Hormones https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 📲 Follow Dr. McCarthy: Instagram: @drbrendanmccarthy TikTok: @drbrendanmccarthy Website: www.protealife.com 💬 Got a question or topic for a future episode? Let us know in the comments!…

Dr. Brendan McCarthy

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Estrone & Cancer: The Truth About “The Forgotten Estrogen” 29:43

לפני 22 ימים29:43

29:43

In Part 3 of the Forgotten Estrogen series, Dr. Brendan McCarthy—Chief Medical Officer of Protea Medical Center in Tempe, Arizona—dives deep into the misunderstood relationship between estrone and cancer. For decades, women have been told to fear estrogen. But is estrogen really the enemy—or is it the environment within the body that determines risk? Dr. McCarthy explains: How estrone functions after menopause Why estrogen became wrongly vilified after the 2002 Nurse’s Health Study The truth about inflammation, insulin resistance, and detox pathways The role of methylation, glutathione, and liver detox in estrogen metabolism What lab markers actually matter (and how to interpret them) Practical ways to support your hormones through nutrition, sleep, and lifestyle This episode is about empowerment through knowledge, not fear. If you’ve ever been confused or afraid of estrogen, this conversation will change how you understand your body and your hormones. Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he’s helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He’s also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you’re ready to take your health seriously, this podcast is a great place to start. 👇 Tap Subscribe to learn more about what’s actually happening in your body, and what to do about it. 📘 Read Dr. McCarthy’s Book: Jump Off the Mood Swing – A Sane Woman’s Guide to Her Crazy Hormones https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 📲 Follow Dr. McCarthy: Instagram: @drbrendanmccarthy TikTok: @drbrendanmccarthy Website: www.protealife.com 💬 Got a question or topic for a future episode? Let us know in the comments!…

Dr. Brendan McCarthy

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Estrone Explained (Part 2): The “Forgotten Estrogen” and Why It’s Not the Bad Guy 32:43

לפני 29 ימים32:43

32:43

In this episode — Part 2 of our Estrone Series — Dr. McCarthy takes a deeper dive into estrone, the often misunderstood and overlooked estrogen. Learn: Why estrone isn’t the “bad” estrogen it’s made out to be How body fat, inflammation, and lifestyle influence estrone levels The connection between estrone, insulin resistance, and breast health Why oral estrogen can worsen symptoms for some women Natural ways to support estrogen balance, including diet, nutrients, and detox pathways Dr. McCarthy explains how understanding estrone can empower women through perimenopause and menopause — and why context and comprehensive lab work matter more than quick fixes. 💬 Have questions about estrone or hormone balance? Drop them in the comments — your feedback helps shape future episodes! Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he’s helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He’s also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you’re ready to take your health seriously, this podcast is a great place to start. 👇 Tap Subscribe to learn more about what’s actually happening in your body, and what to do about it. 📘 Read Dr. McCarthy’s Book: Jump Off the Mood Swing – A Sane Woman’s Guide to Her Crazy Hormones https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 📲 Follow Dr. McCarthy: Instagram: @drbrendanmccarthy TikTok: @drbrendanmccarthy Website: www.protealife.com 💬 Got a question or topic for a future episode? Let us know in the comments!…

Dr. Brendan McCarthy

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Estrone Explained: How Lifestyle & Hormones Impact Women’s Health 32:43

לפני 5 weeks32:43

32:43

In this episode, Dr. Brendan McCarthy, Chief Medical Officer of Protea Medical Center, dives deep into estrone, one of the three key estrogens, and explains why understanding it is crucial for women’s health. Learn about: The differences between estradiol, estriol, and estrone How estrone levels shift during perimenopause and menopause Why oral estrogen can dramatically increase estrone The impact of lifestyle factors like diet, body fat, stress, alcohol, and sedentary behavior on estrogen balance Practical tips to support healthy estrogen metabolism naturally Dr. McCarthy breaks down complex biochemistry in a clear, actionable way so you can take charge of your hormonal health. Citations: 1. Bulun, Serdar E., et al. “Aromatase and Estrogen Biosynthesis in Adipose Tissue.” Endocrine Reviews, vol. 23, no. 3, 2002, pp. 305–342. 2. Labrie, Fernand, et al. “Importance of the Intracrinology of Estrogen Synthesis in Peripheral Tissues in Postmenopausal Women.” Journal of Steroid Biochemistry and Molecular Biology, vol. 118, nos. 4–5, 2010, pp. 273–279. 3. Sasano, Hironobu, and Toshihiko Harada. “Differential Expression of Aromatase and 17β-Hydroxysteroid Dehydrogenase Isoenzymes in Human Tissues.” Journal of Steroid Biochemistry and Molecular Biology, vol. 86, no. 3–5, 2003, pp. 327–333. 4. Yager, James D., and Nancy E. Davidson. “Estrogen Carcinogenesis in Breast Cancer.” New England Journal of Medicine, vol. 354, no. 3, 2006, pp. 270–282. 5. Cavalieri, Ercole L., and Eleanor G. Rogan. “Depurinating Estrogen-DNA Adducts, Mechanisms of Formation, and Prevention.” Clinical Cancer Research, vol. 16, no. 3, 2010, pp. 596–602. 6. Suba, Zsuzsanna. “Circulating Estrogens and Estrogen Metabolism in Obese Women.” Journal of Clinical Endocrinology and Metabolism, vol. 98, no. 11, 2013, pp. 4336–4344. 7. Simpson, Evan R., and Konstanze C. Pike. “Aromatase Expression in Adipose Tissue: Relationship to Obesity and Insulin Resistance.” Endocrinology, vol. 156, no. 9, 2015, pp. 3422–3435. 8. Key, Timothy J., et al. “Circulating Sex Hormones and Breast Cancer Risk Factors in Postmenopausal Women: Reanalysis of 13 Studies.” British Journal of Cancer, vol. 105, no. 5, 2011, pp. 709–722. 9. Stanczyk, Frank Z., et al. “Oral, Transdermal and Injectable Hormone Therapy: Pharmacokinetics and Effects on Estrone/Estradiol Ratios.” Menopause, vol. 24, no. 9, 2017, pp. 1080–1090. 10. Santen, Richard J., et al. “Estrogen Bioidentical Hormone Therapy: Route of Administration and Risk.” Journal of Clinical Endocrinology and Metabolism, vol. 105, no. 7, 2020, pp. 2062–2074. 11. Zeleniuch-Jacquotte, Anne, et al. “Postmenopausal Levels of Estrone, Estradiol, and Estrone Sulfate and Breast Cancer Risk.” Cancer Epidemiology, Biomarkers & Prevention, vol. 23, no. 8, 2014, pp. 1531–1539. 12. Dall, Gabriella V., and Christine L. Clarke. “Local Estrogen Biosynthesis and Signaling in Breast Cancer Progression.” Steroids, vol. 78, no. 7, 2013, pp. 639–646. 13. Heald, Anthony H., et al. “Relationships Between Serum Estrone, Insulin Resistance, and Adiposity in Postmenopausal Women.” Clinical Endocrinology, vol. 67, no. 3, 2007, pp. 340–345. 14. Kuiper, George G. J. M., et al. “Estrogen Receptor β Selectivity of Estriol and Implications for Tissue-Specific Effects.” PNAS, vol. 94, no. 17, 1997, pp. 9105–9110. 15. Michnovicz, Joseph J., et al. “Dietary Indoles and Estrogen Metabolism: Effects of Cruciferous Vegetable Intake.” Journal of Nutrition, vol. 134, no. 12, 2004, pp. 3479S– Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he’s helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He’s also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you’re ready to take your health seriously, this podcast is a great place to start. 👇 Tap Subscribe to learn more about what’s actually happening in your body, and what to do about it. 📘 Read Dr. McCarthy’s Book: Jump Off the Mood Swing – A Sane Woman’s Guide to Her Crazy Hormones https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 📲 Follow Dr. McCarthy: Instagram: @drbrendanmccarthy TikTok: @drbrendanmccarthy Website: www.protealife.com 💬 Got a question or topic for a future episode? Let us know in the comments!…

Dr. Brendan McCarthy

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Healing the Divide Between MAHA & MAMA 17:40

לפני 6 weeks17:40

17:40

In this heartfelt episode, Dr. Brendan McCarthy dives deep into why women are turning away from conventional medicine and seeking care in alternative spaces. He explores the growing Make America Healthy Again (MAHA) and Make America Medical Again (MAMA) movements, sharing his perspective as a naturopathic medical doctor trained in both conventional and integrative medicine. Dr. McCarthy discusses empathy in healthcare, accountability to patients, and the importance of bridging the gap between modern medicine and natural approaches. This episode is an honest look at what real medicine should feel like—human, compassionate, and deeply connected. 🔹 Topics Covered: Why women are leaving conventional medicine The rise of MAHA and MAMA movements How empathy and validation heal where prescriptions can’t Building accountability and integrity in patient care Bridging the divide between natural and conventional medicine Citations: https://drive.google.com/file/d/1R7oRXvuVDl5pW-pGXtfXXs0Ue3L11whZ/view?usp=sharing Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he’s helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He’s also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you’re ready to take your health seriously, this podcast is a great place to start. 👇 Tap Subscribe to learn more about what’s actually happening in your body, and what to do about it. 📘 Read Dr. McCarthy’s Book: Jump Off the Mood Swing – A Sane Woman’s Guide to Her Crazy Hormones https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 📲 Follow Dr. McCarthy: Instagram: @drbrendanmccarthy TikTok: @drbrendanmccarthy Website: www.protealife.com 💬 Got a question or topic for a future episode? Let us know in the comments!…

Dr. Brendan McCarthy

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Why Conventional Medicine Failed Women 23:06

לפני 7 weeks23:06

23:06

In this powerful episode, Dr. McCarthy continues his “Make America Healthy Again” series — exploring how conventional medicine has failed women through dismissal, invalidation, and profit-driven care. He discusses why so many women are turning to online influencers and alternative medicine for answers, and how we can begin to reconcile modern medicine with true, compassionate healthcare. 👉 Topics covered: The systemic dismissal of women’s symptoms How short medical visits and profit models harm patients The rise of “Make America Healthy Again” culture The dangers of influencer-driven supplement marketing Why reconciliation between women and medicine is essential 🎧 A thoughtful, research-backed conversation that challenges the system — and advocates for women’s health, time, and trust. Citations: https://drive.google.com/file/d/1AygX2JSGLMyDrQt5WW6v3Xk4m1lhPblE/view Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he’s helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He’s also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you’re ready to take your health seriously, this podcast is a great place to start. 👇 Tap Subscribe to learn more about what’s actually happening in your body, and what to do about it. 📘 Read Dr. McCarthy’s Book: Jump Off the Mood Swing – A Sane Woman’s Guide to Her Crazy Hormones https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 📲 Follow Dr. McCarthy: Instagram: @drbrendanmccarthy TikTok: @drbrendanmccarthy Website: www.protealife.com 💬 Got a question or topic for a future episode? Let us know in the comments!…

Dr. Brendan McCarthy

1
How Medicine Lost Its Way with Women 28:32

לפני 8 weeks28:32

28:32

In this episode, I dive deep into “Mama vs. Maha” — the Make America Medical Again movement versus the Make America Healthy Again movement — and explore how both emerged from a broken medical system. We’ll trace how modern medicine drifted from its original purpose, focusing more on economics than empathy, and how that shift has profoundly impacted women’s health over the past 60 years. From the “Valium era” to SSRIs and Ambien, I break down how systemic neglect, profit motives, and regulatory failures alienated women from traditional care — and what it will take to restore trust. This episode is personal, reflective, and at times somber — but it’s an important conversation about accountability, reconciliation, and rebuilding the heart of medicine. References: https://drive.google.com/file/d/1mQKU7VpiT5KhXCFFLYtdVoWFAjKRi16J/view?usp=sharing Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he’s helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He’s also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you’re ready to take your health seriously, this podcast is a great place to start. 👇 Tap Subscribe to learn more about what’s actually happening in your body, and what to do about it. 📘 Read Dr. McCarthy’s Book: Jump Off the Mood Swing – A Sane Woman’s Guide to Her Crazy Hormones https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 📲 Follow Dr. McCarthy: Instagram: @drbrendanmccarthy TikTok: @drbrendanmccarthy Website: www.protealife.com 💬 Got a question or topic for a future episode? Let us know in the comments!…

Dr. Brendan McCarthy

1
Understanding the Divide in Modern Medicine 19:57

לפני 9 weeks19:57

19:57

Join Dr. Brendan McCarthy, as he dives into Part 2 of our series on understanding the divide in modern medicine. In this episode, Dr. McCarthy explores: How education, corporate influence, and lobbying have shaped medicine and nutrition advice The history and impact of the food pyramid and dietary guidelines Why trust in traditional medicine has eroded and how alternative approaches gained popularity The role of pharmaceutical advertising and conference influence on medical practice Steps to rebuild trust and prioritize patient-centered care Dr. McCarthy emphasizes accountability, understanding science objectively, and always keeping the patient’s well-being at the center of care. 📌 Citation / References: Steinman, Michael A., and Jerome P. Kassirer. “Is Continuing Medical Education a Drug-Promotion Tool? YES.” Canadian Family Physician, vol. 53, no. 10, 2007, pp. 1650–1652. PMC, https://pmc.ncbi.nlm.nih.gov/articles/PMC2231419. ⸻ 2. Bowman, Marjorie A., and David L. Pearle. “Changes in Drug Prescribing Patterns Related to Commercial Company Funding of Continuing Medical Education.” Journal of Continuing Education in the Health Professions, vol. 8, no. 1, 1988, pp. 13–20. Lippincott Williams & Wilkins, https://journals.lww.com/jcehp/fulltext/1988/08010/changes_in_drug_prescribing_patterns_related_to.3.aspx. ⸻ 3. Bowman, Marjorie A., and David L. Pearle. “Industry-Sponsored Grand Rounds and Prescribing Behavior.” Journal of the American Medical Association, vol. 283, no. 3, 2000, pp. 373–380. ResearchGate, https://www.researchgate.net/publication/12077958_Industry-Sponsored_Grand_Rounds_and_Prescribing_Behavior. ⸻ 4. Fickweiler, Frederike, Udo Fickweiler, and Klaus Urbach. “Interactions between Physicians and the Pharmaceutical Industry Generally and Sales Representatives Specifically and Their Association with Physicians’ Attitudes and Prescribing Habits: A Systematic Review.” BMJ Open, vol. 7, no. 9, 2017, e016408. BMJ Publishing Group, https://bmjopen.bmj.com/content/7/9/e016408. ⸻ 5. Fugh-Berman, Adriane. “May I Have the Sting? Cutting CME’s Ties to Pharma.” AMA Journal of Ethics, vol. 8, no. 6, 2006, pp. 356–360. American Medical Association, https://journalofethics.ama-assn.org/article/may-sting-bit-cutting-cmes-ties-pharma/2006-06 Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he’s helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He’s also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you’re ready to take your health seriously, this podcast is a great place to start. 👇 Tap Subscribe to learn more about what’s actually happening in your body, and what to do about it. 📘 Read Dr. McCarthy’s Book: Jump Off the Mood Swing – A Sane Woman’s Guide to Her Crazy Hormones https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 📲 Follow Dr. McCarthy: Instagram: @drbrendanmccarthy TikTok: @drbrendanmccarthy Website: www.protealife.com 💬 Got a question or topic for a future episode? Let us know in the comments!…

Dr. Brendan McCarthy

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Why Patients Lose Trust in Medicine | Radical Transparency 20:32

לפני 10 weeks20:32

20:32

In this episode, Dr. Brendan McCarthy, Chief Medical Officer of Protea Medical Center, opens up about why so many patients lose trust in traditional, insurance-based medical care—and why they often turn exclusively to alternative medicine. Dr. McCarthy shares personal experiences and patient stories that reveal the deeper issues in today’s healthcare system: short appointment times, lack of empathy, profit-driven models, and the powerful role of storytelling in alternative health. This conversation is about more than medicine—it’s about empathy, validation, and radical transparency in how we care for one another. In this episode you’ll learn: Why patients often reject pharmaceuticals (even when safe & effective) The role of empathy and time in building trust How alternative medicine wins hearts through stories Why managed care models fail both patients and providers How we can rebuild trust in healthcare through radical transparency Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he’s helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He’s also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you’re ready to take your health seriously, this podcast is a great place to start. 👇 Tap Subscribe to learn more about what’s actually happening in your body, and what to do about it. 📘 Read Dr. McCarthy’s Book: Jump Off the Mood Swing – A Sane Woman’s Guide to Her Crazy Hormones https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 📲 Follow Dr. McCarthy: Instagram: @drbrendanmccarthy TikTok: @drbrendanmccarthy Website: www.protealife.com 💬 Got a question or topic for a future episode? Let us know in the comments!…

Dr. Brendan McCarthy

1
Why I Practice Medicine Differently 21:16

לפני 11 weeks21:16

21:16

In this episode, I open up about my personal journey into medicine, how my son’s health crisis during medical school shaped the doctor I am today, and why I believe in practicing medicine with time, care, and accountability. As a licensed naturopathic medical doctor and primary care provider, I share how I balance conventional treatments with holistic approaches, and why I think medicine needs both science and humanity. You’ll hear: The personal story that drove me to become the kind of doctor I am today Why I spend extra time with patients and focus on building trust The strengths and challenges of both conventional and alternative medicine How patients can learn who to trust in today’s confusing healthcare world Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he’s helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He’s also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you’re ready to take your health seriously, this podcast is a great place to start. 👇 Tap Subscribe to learn more about what’s actually happening in your body, and what to do about it. 📘 Read Dr. McCarthy’s Book: Jump Off the Mood Swing – A Sane Woman’s Guide to Her Crazy Hormones https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 📲 Follow Dr. McCarthy: Instagram: @drbrendanmccarthy TikTok: @drbrendanmccarthy Website: www.protealife.com 💬 Got a question or topic for a future episode? Let us know in the comments!…

Dr. Brendan McCarthy

1
From Self-Silencing to Healing: Women's Health, Stress & Weight Gain 28:35

לפני 12 weeks28:35

28:35

In this powerful series finale, Dr. Brendan McCarthy, Chief Medical Officer of Protea Medical Center, shares a personal story about the humble beginnings of his practice—and then dives deep into a critical but often overlooked topic in medicine: self-silencing in women and how it profoundly impacts health. In this episode, you'll learn: How emotional suppression and chronic stress affect weight gain, fertility, autoimmunity, and thyroid function Why simply telling women to “eat less” or “relax” is not real medicine—and what actually works The role of intermittent fasting, hormonal support, and therapy in restoring health How to identify self-silencing behaviors and start healing from the inside out A discussion of GLP-1s, LDN, cold plunges, testosterone, thyroid labs, and more A call for modern medicine to return to true, whole-person care Whether you're a patient, physician, or just curious about the future of compassionate medicine—this one’s for you. Citations: https://academic.oup.com/mend/article/15/11/1864/2747880 https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2012.00177/full Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he’s helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He’s also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you’re ready to take your health seriously, this podcast is a great place to start. 👇 Tap Subscribe to learn more about what’s actually happening in your body, and what to do about it. 📘 Read Dr. McCarthy’s Book: Jump Off the Mood Swing – A Sane Woman’s Guide to Her Crazy Hormones https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 📲 Follow Dr. McCarthy: Instagram: @drbrendanmccarthy TikTok: @drbrendanmccarthy Website: www.protealife.com 💬 Got a question or topic for a future episode? Let us know in the comments!…

Dr. Brendan McCarthy

1
The Silent Stress That’s Harming Women’s Health 29:47

לפני 13 weeks29:47

29:47

Why do so many women struggle with autoimmune issues, fertility challenges, cardiovascular disease, and weight gain—despite following medical advice? In this episode, Dr. Brendan McCarthy, NMD, explores the overlooked connection between self-silencing—the habit of suppressing your voice, needs, and emotions—and women’s health. Drawing on years of patient care and research, he explains how chronic stress from silencing yourself impacts the body at a biochemical level, and what you can do about it. You’ll learn: ✔️ How self-silencing triggers stress pathways that worsen inflammation and disease ✔️ Why heart rate variability is a powerful tool for tracking stress ✔️ Simple, science-backed therapies—from cold plunging to nutrition to breathing techniques ✔️ How physicians can address both the cause and the symptoms of stress-related illness ✔️ What treatments may help stabilize autoimmunity, cardiovascular risk, and fertility issues This episode wraps up Dr. McCarthy’s series on self-silencing and offers practical strategies to support healing while doing the deeper inner work. Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he’s helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He’s also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you’re ready to take your health seriously, this podcast is a great place to start. 👇 Tap Subscribe to learn more about what’s actually happening in your body, and what to do about it. 📘 Read Dr. McCarthy’s Book: Jump Off the Mood Swing – A Sane Woman’s Guide to Her Crazy Hormones https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 📲 Follow Dr. McCarthy: Instagram: @drbrendanmccarthy TikTok: @drbrendanmccarthy Website: www.protealife.com 💬 Got a question or topic for a future episode? Let us know in the comments!…

Dr. Brendan McCarthy

1
The Hidden Link Between Self-Silencing and Fertility 18:42

לפני 14 weeks18:42

18:42

In this episode, Dr. Brendan McCarthy, Chief Medical Officer at Protea Medical Center in Tempe, Arizona, explores how self-silencing—the cultural pressure for women to suppress their voices and needs—can directly affect fertility. Dr. McCarthy discusses: The emotional toll of self-silencing on women’s identity and value How chronic stress impacts ovulation, progesterone, and conception Why the medical system often overlooks stress as a factor in infertility A more compassionate, integrative approach to fertility care This episode is part of a larger series on self-silencing and women’s health. If you’ve struggled with fertility or felt unheard in medical settings, this conversation offers insight and hope. Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he’s helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He’s also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you’re ready to take your health seriously, this podcast is a great place to start. 👇 Tap Subscribe to learn more about what’s actually happening in your body, and what to do about it. 📘 Read Dr. McCarthy’s Book: Jump Off the Mood Swing – A Sane Woman’s Guide to Her Crazy Hormones https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 📲 Follow Dr. McCarthy: Instagram: @drbrendanmccarthy TikTok: @drbrendanmccarthy Website: www.protealife.com 💬 Got a question or topic for a future episode? Let us know in the comments!…

Dr. Brendan McCarthy

1
Progesterone Delivery Methods Explained: How It Actually Works in Your Body 30:47

לפני 30 weeks30:47

30:47

Welcome to the podcast with Dr. Brendan McCarthy! Explore how progesterone travels through the body depending on the method of delivery—oral, transdermal, or injection. Dr. McCarthy explains why certain forms may not be effective for all patients and discusses how the body metabolizes progesterone, influencing its therapeutic impact. This episode is essential for anyone considering or currently on hormone replacement therapy. Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Hurst BS, Jones AI, Elliot M, Marshburn PB, Matthews ML. Absorption of vaginal estrogen cream during sexual intercourse: a prospective, randomized, controlled trial. J Reprod Med. 2008;53(1):29–32. PMID: 18251358 Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-... -More Links- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com…

Dr. Brendan McCarthy

1
Answering Your Hormone Questions: Progesterone Reactions, MTHFR, Estrogen Detox & More 33:35

לפני 31 weeks33:35

33:35

Welcome to the podcast with Dr. Brendan McCarthy! Today’s episode is all about answering YOUR submitted questions — real concerns from real women — about hormone therapy, reverse responses to progesterone, MTHFR, estrogen detoxification, and more. This episode is packed with insights to help you better understand your body and your options. Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-... -More Links- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com…

Dr. Brendan McCarthy

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Progesterone, Testosterone & HRT Questions You’re Afraid to Ask 42:12

לפני 32 weeks42:12

42:12

Welcome to the podcast! In this deeply personal Q&A episode, Dr. Brendan McCarthy—Chief Medical Officer at Protea Medical Center—responds to your most powerful and vulnerable questions about hormone replacement therapy, including: - Why some women reverse-respond to progesterone - What to do when testosterone creams trigger migraines - How to safely navigate HRT with MTHFR or methylation issues - The emotional toll of being dismissed by doctors - Why libido and vitality matter at every age - How to advocate for yourself in a broken healthcare system This episode is about more than medicine—it's about being seen, finding hope, and reclaiming the quality of life you deserve. Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-... -More Links- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com…

Dr. Brendan McCarthy

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When Progesterone Backfires: Understanding Reverse Responders 16:14

לפני 33 weeks16:14

16:14

Welcome to the podcast with Dr. Brendan McCarthy! Welcome to Part 3. In this episode, Dr. McCarthy dives deep into the complex world of reverse responders—women who experience increased anxiety or worsened symptoms from progesterone instead of the calming effects it typically provides. If you’ve felt forgotten or unsupported in your hormone journey—this episode is for you. Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-... -More Links- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com…

Dr. Brendan McCarthy

1
When Progesterone Backfires: The Hidden Link Between Hormones, Anxiety & Trauma 16:43

לפני 34 weeks16:43

16:43

Welcome to the podcast with Dr. Brendan McCarthy! While progesterone is often prescribed for its calming and hormone-balancing effects, some women experience the exact opposite—increased anxiety, depression, and emotional instability. This phenomenon, known as reverse responding, is more common than many realize. In this episode we explore: The neurological effects of progesterone and why it can backfire The role of allopregnanolone and the GABA receptor How trauma, PTSD, and adverse childhood experiences impact hormonal response Safer and more personalized treatment options—including transrectal delivery, low-dose titration, and supportive therapies like EMDR and testosterone modulation Why addressing hormone imbalances requires more than symptom management—it requires a deeper understanding of the brain-body connection This science-driven, trauma-informed conversation offers vital insights for any woman who’s felt worse after starting progesterone—and for the healthcare providers who want to help them. Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-... -More Links- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com…

Dr. Brendan McCarthy

1
Why Progesterone Doesn’t Work for Everyone 18:02

לפני 35 weeks18:02

18:02

Welcome to the podcast with Dr. Brendan McCarthy! Today he addresses a topic many women have been waiting to hear more about: why some people don't tolerate progesterone well. Often overlooked in both conventional and alternative medicine, "reverse responders" experience heightened anxiety, insomnia, or mood shifts when taking progesterone — a reaction that defies the standard approach. Dr. McCarthy explores the science behind these responses, the emotional toll of being dismissed, and why deeper investigation and individualized care are essential. This episode is the first in a multi-part series where Dr. McCarthy shares: • What progesterone is supposed to do in the body • Why it can sometimes cause adverse effects • The importance of understanding hormone-brain interactions • A more compassionate and evidence-based approach to hormone therapy If you or someone you love has struggled with hormone treatments, this episode offers insight, validation, and a path forward. Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-... -More Links- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com…

Dr. Brendan McCarthy

1
Migraine Series Q&A 30:36

לפני 36 weeks30:36

30:36

Welcome to the podcast with Dr. Brendan McCarthy! In this episode we're wrapping up our migraine series by answering your most frequently asked questions. Dr. Brendan McCarthy, Chief Medical Officer at Protea Medical Center, dives deep into the science behind progesterone, its effects on the brain, and why some people experience negative reactions. He also discusses estrogen therapy, common side effects, and why personalized medicine is key. Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-... -More Links- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com…

Dr. Brendan McCarthy

1
Triptans and Beyond: Understanding the True Causes of Migraines 20:08

לפני 37 weeks20:08

20:08

Welcome to the podcast with Dr. Brendan McCarthy! In this episode, we dive into the complexities of migraines, particularly the role of triptans in treating them. Dr. McCarthy addresses a common misconception about migraine pathophysiology, discusses the importance of lifestyle and genetic factors, and explains why understanding the root causes of migraines is crucial for effective treatment. He emphasizes the importance of a comprehensive approach, going beyond just using medications like triptans and considering factors such as serotonin levels, magnesium deficiency, and food sensitivities. Tune in to learn more about the intricate science behind migraines and the personalized strategies that can help manage them effectively. Credit & Resources The infographic used in this video is from the Anxiety & Depression Association of America (ADAA). Learn more about anxiety, depression, and mental health resources at adaa.org. Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-... -More Links- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com…

Dr. Brendan McCarthy

1
Unlocking the Root Cause of Migraines: The Role of Progesterone and GABA 21:24

לפני 38 weeks21:24

21:24

Welcome to the podcast with Dr. Brendan McCarthy! In this episode we dive deep into the root causes of migraines in women, with a focus on the powerful role of progesterone and the GABA pathway. Learn why simply treating symptoms with medication isn’t enough and how understanding hormone balance can lead to long-term relief. This is part two of our migraine series, where we explore how estrogen and progesterone fluctuations impact brain chemistry and neural inflammation. If you’re tired of being dismissed by doctors and want to better advocate for your health, this episode is for you. Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 --More Links-- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com Research Cited: Sripada RK, Marx CE, King AP, Rampton JC, Ho SS, Liberzon I. Allopregnanolone elevations following pregnenolone administration are associated with enhanced activation of emotion regulation neurocircuits. Biol Psychiatry. 2013 Jun 1;73(11):1045-53. doi: 10.1016/j.biopsych.2012.12.008. Epub 2013 Jan 21. PMID: 23348009; PMCID: PMC3648625. Monteleone, Patrizia, et al. "Allopregnanolone concentrations and premenstrual syndrome." European journal of endocrinology 142.3 (2000): 269-273…

Dr. Brendan McCarthy

1
The Role of Estrogen in Migraines: Understanding the Link & Treatment Options 21:24

לפני 38 weeks21:24

21:24

Welcome to the podcast with Dr. Brendan McCarthy! In this episode we go over the connection between estrogen and migraines. He explores how hormone fluctuations can trigger migraines, the role of serotonin, and how proper medical testing can lead to better treatment options. Dr. McCarthy also addresses common failures in traditional medicine, the importance of a full neurological workup, and why balancing estrogen is key to overall health. Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy is the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-... -More Links- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com Research Cited: Körtési, Tamás, Eleonóra Spekker, and László Vécsei. "Exploring the tryptophan metabolic pathways in migraine-related mechanisms." Cells 11.23 (2022): 3795.…

Dr. Brendan McCarthy

1
Understanding Headaches 13:34

לפני 38 weeks13:34

13:34

Welcome to the podcast with Dr. Brendan McCarthy! In this episode we dive into headaches—particularly how women suffer from them more frequently than men. If you’ve been dealing with headaches that no one seems to understand, you’re not alone. This series is designed to offer insight and actionable advice, empowering you with the information you need to address the root causes of your pain. Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 --More Links-- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com…

Dr. Brendan McCarthy

1
Your Voice Matters—Let’s Talk Menopause 30:13

לפני 41 weeks30:13

30:13

Welcome to the podcast with Dr. Brendan McCarthy, Chief Medical Officer of Protea Medical Center in Tempe, Arizona. Your feedback and comments shape the discussions we have here—because your voice matters. In this episode, Dr. McCarthy addresses some of the most common questions and misconceptions about menopause and hormone replacement therapy (HRT). He breaks down the science, clears up misunderstandings, and emphasizes the importance of personalized care—whether you choose HRT or not. This episode is part of an ongoing series on menopause treatment, driven by the real concerns and questions from listeners like you. Dr. McCarthy explains the role of estrogen in health, the impact of stopping hormone therapy, and alternative approaches to managing symptoms like bone loss, cholesterol changes, and mood fluctuations. Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 --More Links-- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com…

Dr. Brendan McCarthy

1
Menopause & Hormone Therapy: Treatment Pt. 2 16:52

לפני 42 weeks16:52

16:52

Welcome to the podcast with Dr. Brendan McCarthy! We continue our menopause series as we dive into the treatment segment! Struggling with menopause symptoms like hot flashes, mood swings, or sleep issues? Hormone therapy (HRT) could be the solution! In this video, we break down how hormone treatment works, its benefits, risks, and who it’s best for. Learn the facts and take control of your health during menopause! This is Part 2 of 2 for Treatment Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 --More Links-- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com…

Dr. Brendan McCarthy

1
Menopause & Hormone Therapy: Treatment Pt. 1 14:36

לפני 42 weeks14:36

14:36

Welcome to the podcast with Dr. Brendan McCarthy! We continue our menopause series as we dive into the treatment segment! Struggling with menopause symptoms like hot flashes, mood swings, or sleep issues? Hormone therapy (HRT) could be the solution! In this video, we break down how hormone treatment works, its benefits, risks, and who it’s best for. Learn the facts and take control of your health during menopause! This is Part 1 of 2 for Treatment Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 --More Links-- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com…

Dr. Brendan McCarthy

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How to Recognize the Signs of Menopause: Symptoms & Diagnosis Explained 25:09

לפני 44 weeks25:09

25:09

Welcome to the podcast with Dr. Brendan McCarthy! Are you experiencing changes in your body and wondering if it might be menopause? I’ll guide you through the key signs and symptoms of menopause, the role of hormonal changes, lab values and how to approach an accurate diagnosis. Understanding your body is the first step to managing this transition effectively. This is Part 2 of 4 Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 --More Links-- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com…

Dr. Brendan McCarthy

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Self-Silencing in Women: The Hidden Link to Stress, Hormones & Heart Health 28:33

לפני 15 weeks28:33

28:33

Why do so many women struggle with stress-related health issues without ever speaking up? In this episode, Dr. Brendan McCarthy continues his series on self-silencing in women—a powerful yet often overlooked cultural and psychological pattern. Dr. McCarthy breaks down: What “self-silencing” really means and how it shows up in everyday life The four categories of self-silencing How chronic stress and emotional suppression affect hormones, fertility, and cardiovascular health Why women face higher risks of heart disease when these patterns go unaddressed What men can do to better support their partners during PMS, perimenopause, and menopause This conversation is about more than symptoms—it’s about validation, advocacy, and the urgent need to recognize how cultural conditioning impacts women’s health. Citations: Jack, D. C., & Dill, D. (1992). The Silencing the Self Scale: Schemas of intimacy associated with depression in women. Psychology of Women Quarterly, 16(1), 97–106. • Jack, D. C. (1999). Silencing the self: Inner dialogues and outer realities. Harvard University Press. • Jack, D. C. (2011). Reflections on the silencing the self scale and its origins. Psychology of Women Quarterly, 35(3), 523–529. • Jakubowski, K. P., Barinas-Mitchell, E., et al. (2022). The cardiovascular cost of silence: Self-silencing and carotid atherosclerosis. Annals of Behavioral Medicine, 56(3), 282–293. • Ussher, J. M. (2004). Premenstrual syndrome and self-policing. Social Theory & Health, 2(1), 56–77. • Ussher, J. M. (2013). Diagnosing difficult women. Feminism & Psychology, 23(1), 63–77. • Beauboeuf-Lafontant, T. (2008). Listening past the lies. Qualitative Sociology, 31(2), 105–124. • Rozanski, A. (2014). Behavioral cardiology. Circulation, 129(25), 2509–2516. 1. Jack & Dill (1992) – Developed Silencing the Self Scale. Linked to depression and poor health outcomes. 2. Framingham Offspring Study (Jack, 2011) – Women with high self-silencing had ↑ heart disease and premature death. 3. Jakubowski et al. (2022, Annals of Behavioral Medicine) – Self-silencing predicted ↑ carotid atherosclerosis in midlife women. 4. Beauboeuf-Lafontant (2008, Qualitative Sociology) – Black women’s depression tied to silencing under cultural expectations of strength. 5. Ussher (2004, 2013, 2023) – Purity/self-policing associated with self-blame and somatic illness pathways. 6. Rasmussen (2014) – Self-silencing linked to anger suppression, leading to somatic symptoms. 7. Peterson (2015) – Shame and silence in purity narratives obstruct preventive health care. 8. CRP & Stress Studies – High CRP consistently linked to psychosocial stress (Rozanski, 2014, Circulation). Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he’s helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He’s also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you’re ready to take your health seriously, this podcast is a great place to start. 👇 Tap Subscribe to learn more about what’s actually happening in your body, and what to do about it. 📘 Read Dr. McCarthy’s Book: Jump Off the Mood Swing – A Sane Woman’s Guide to Her Crazy Hormones https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 📲 Follow Dr. McCarthy: Instagram: @drbrendanmccarthy TikTok: @drbrendanmccarthy Website: www.protealife.com 💬 Got a question or topic for a future episode? Let us know in the comments!…

Dr. Brendan McCarthy

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Self-Silencing, Stress & Autoimmunity in Women 29:59

לפני 16 weeks29:59

29:59

In this episode, Dr. Brendan McCarthy explores how self-silencing behaviors—putting others first, suppressing your own needs, and avoiding conflict—can contribute to chronic stress and trigger autoimmune conditions in women. From the science of immune misfires to the cultural pressures women face, Dr. McCarthy shares how deep, patient-centered care goes beyond prescriptions to address the root causes of illness. He discusses the link between trauma, vagal tone, hormone balance, inflammation, and lifestyle habits—and why breaking the self-silencing cycle can be a powerful step toward healing. If you’ve been told “your labs look fine” but you still don’t feel well, this conversation will help you understand why. Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he’s helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He’s also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you’re ready to take your health seriously, this podcast is a great place to start. 👇 Tap Subscribe to learn more about what’s actually happening in your body, and what to do about it. 📘 Read Dr. McCarthy’s Book: Jump Off the Mood Swing – A Sane Woman’s Guide to Her Crazy Hormones https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 📲 Follow Dr. McCarthy: Instagram: @drbrendanmccarthy TikTok: @drbrendanmccarthy Website: www.protealife.com 💬 Got a question or topic for a future episode? Let us know in the comments!…

Dr. Brendan McCarthy

1
The Hidden Cost of Self-Silencing: How It Impacts Women’s Health 27:01

לפני 17 weeks27:01

27:01

Welcome to the first episode in a five-part series on self-silencing and its profound effect on women’s health. I’m Dr. Brendan McCarthy, Chief Medical Officer at Protea Medical Center, and in this episode, I break down how self-silencing — the learned suppression of one’s needs, emotions, and voice — directly influences weight gain, hormone disruption, autoimmunity, cardiovascular risk, and more. This is a deeply personal and evidence-backed conversation rooted in decades of clinical experience and medical research. I discuss real patient patterns, the emotional layers behind common health complaints, and why this silent epidemic deserves more space in medicine. If you or someone you love has ever struggled with feeling unheard, unseen, or overwhelmed by caretaking roles, this is for you. Citations: 13] Jakubowski, K. P., Barinas-Mitchell, E., Chang, Y.-F., Maki, P. M., Matthews, K. A., & Thurston, R. C. (2021). The Cardiovascular Cost of Silence: Relationships Between Self-silencing and Carotid Atherosclerosis in Midlife Women. *Annals of Behavioral Medicine, 56*(3), 282–290. DOI: 10.1093/abm/kaab046 [27] Eyal, M. (2023, October 3). Self-Silencing Is Making Women Sick. *TIME*. [5] Jack, D. C. (2010, March 29). Silencing the Self Theory. *OUPblog*. Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he’s helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He’s also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you’re ready to take your health seriously, this podcast is a great place to start. 👇 Tap Subscribe to learn more about what’s actually happening in your body, and what to do about it. 📘 Read Dr. McCarthy’s Book: Jump Off the Mood Swing – A Sane Woman’s Guide to Her Crazy Hormones https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 📲 Follow Dr. McCarthy: Instagram: @drbrendanmccarthy TikTok: @drbrendanmccarthy Website: www.protealife.com 💬 Got a question or topic for a future episode? Let us know in the comments!…

Dr. Brendan McCarthy

1
Men & Fertility: What No One Tells You About Showing Up for Her 24:38

לפני 18 weeks24:38

24:38

In today’s episode, we’re talking about the role men play in fertility and women’s health. Too often, the fertility journey places the burden entirely on women, physically, emotionally, and medically. Dr. McCarthy unpacks why that’s both inaccurate and damaging, and shares what true masculinity looks like during this chapter: support, presence, and courage. From hormone imbalances and sperm health to the overlooked emotional toll men face, this episode is a candid call for men to stay in the room—with their partners and with themselves. 🔍 Topics covered: Why the fertility industry fails couples The emotional withdrawal reflex many men experience Microplastics, testosterone, and sperm quality What lab work men should request The truth about aging and male fertility Real steps to support your partner and reclaim your role Whether you're navigating fertility, supporting someone who is, or simply want to be a better partner, this episode offers insight and grounded advice. Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he’s helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He’s also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you’re ready to take your health seriously, this podcast is a great place to start. 👇 Tap Subscribe to learn more about what’s actually happening in your body, and what to do about it. 📘 Read Dr. McCarthy’s Book: Jump Off the Mood Swing – A Sane Woman’s Guide to Her Crazy Hormones https://www.amazon.com/Jump-Off-Mood-Swing-Hormones/dp/0999649604 📲 Follow Dr. McCarthy: Instagram: @drbrendanmccarthy TikTok: @drbrendanmccarthy Website: www.protealife.com 💬 Got a question or topic for a future episode? Let us know in the comments!…

Dr. Brendan McCarthy

1
Male Fertility & Emotional Avoidance: Why Men Need to Show Up 26:41

לפני 19 weeks26:41

26:41

Welcome to the podcast with Dr. Brendan McCarthy! In this episode, Dr. McCarthy opens up about the psychological hurdles men face when it comes to reproductive health, how avoidance can create deep relationship wounds, and why it's critical for male partners to step into fertility conversations with courage and compassion. He breaks down: ✔️ The emotional weight women carry in fertility journeys ✔️ How low testosterone and sperm count influence male behavior ✔️ Why fertility has been unfairly framed as a “women’s issue” ✔️ The connection between masculinity and fertility shame ✔️ What men can do TODAY to show up differently Whether you're a woman looking for tools to help your partner understand the burden you carry, or a man ready to take ownership of your role in this shared journey, this episode offers insight, validation, and hope. 💻 Learn more at https://protealife.com Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-... -More Links- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com…

Dr. Brendan McCarthy

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Understanding PMS: A Guide for Men on Hormones, Relationships & Self-Silencing 27:05

לפני 20 weeks27:05

27:05

Welcome to the podcast with Dr. Brendan McCarthy! PMS isn’t just a hormone issue—it affects relationships too. In this episode, Dr. McCarthy breaks down how hormone shifts impact emotions, communication, and connection. It’s a message for men who want to understand what’s really going on—and how to show up better. 💡 Topics: Why PMS can trigger relationship tension The science behind progesterone and mood How self-silencing builds resentment What actually helps (and what doesn’t) If this episode helps, share it with someone who needs to hear it. 💻 Learn more at https://protealife.com Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-... -More Links- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com…

Dr. Brendan McCarthy

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Why Your Doctor Says You're "Fine" (When You're Actually Not) | Testosterone Q&A Pt. 2 27:25

לפני 21 weeks27:25

27:25

Welcome to the podcast with Dr. Brendan McCarthy! Today he continues answering your most pressing questions about testosterone and hormone therapy in Part 2 of our Testosterone Q&A series. In this episode, Dr. McCarthy dives into: Why your labs can look "normal" while you still feel terrible The difference between DHEA and actual testosterone therapy The role of sex hormone-binding globulin (SHBG) in blocking free testosterone The impact of chronic stress on hormone balance Why testosterone creams might not be effective for everyone How estrogen levels affect bone density and hormone optimization 🧬 Featuring insights backed by clinical experience and scientific literature, including: 🔬 Citations Zhu, Z., Zhao, J., Fang, Y. et al. (2021). Association between serum estradiol level, sex hormone binding globulin level, and bone mineral density in middle-aged postmenopausal women. J Orthop Surg Res 16, 648. https://doi.org/10.1186/s13018-021-02799-3 Reginster, J.Y., et al. (1992). Minimal levels of serum estradiol prevent postmenopausal bone loss. Calcif Tissue Int, 51(5), 340–343. https://doi.org/10.1007/BF00316876 💻 Learn more at https://protealife.com Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-... -More Links- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com…

Dr. Brendan McCarthy

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Testosterone in Women: FSH, Hair Loss & Real Questions Answered 22:34

לפני 22 weeks22:34

22:34

Welcome to the podcast with Dr. Brendan McCarthy! In this episode, I’ll be responding to your questions and comments. As always, thank you for being part of this community. Your questions fuel these episodes — and I’m honored to keep showing up for you. 🧪 Have questions about your labs? Drop them in the comments — I may cover them in the next episode. 💬 Yes, I do read them (even in movie previews). Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-... -More Links- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com…

Dr. Brendan McCarthy

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What We’re Learning About TRT and Breast Cancer Risk 23:12

לפני 23 weeks23:12

23:12

Welcome to the podcast with Dr. Brendan McCarthy! In this episode, he dives deep into the powerful potential, and the necessary precautions, of testosterone replacement therapy (TRT) in women. He shares why this once-taboo treatment is gaining traction, how it may reduce the risk of breast cancer by up to 50%, and why lab testing and clinical nuance are absolutely non-negotiable. Dr. McCarthy also addresses medical betrayal, the rise of influencer-driven misinformation, and what it means to receive care rooted in science, safety, and trust. If you've ever been confused, dismissed, or overwhelmed by hormone therapy conversations, this one’s for you. 🧬 Topics covered: TRT’s anti-proliferative effects on breast tissue The importance of lab work and metabolite monitoring DHT, estradiol, and aromatization explained The ethical issues around "lab-free" prescribing Why nuance matters more than ever in women’s hormone care Citation: https://drive.google.com/file/d/11EPfPIotgAeCTr69wHGvErBNafGUipF5/view?usp=sharing Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-... -More Links- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com…

Dr. Brendan McCarthy

1
Why I Always Run Labs Before Hormone Therapy: The Real Risks of Skipping FSH 21:12

לפני 24 weeks21:12

21:12

Welcome to the podcast with Dr. Brendan McCarthy! In this deeply personal episode, he shares why lab work—especially testing FSH (Follicle Stimulating Hormone)—is non-negotiable in hormone replacement therapy. This is not about gatekeeping. It’s about understanding. It’s about caring. Dr. McCarthy recounts a formative memory of meeting a woman who underwent surgical menopause and was never told what would happen to her body afterward. That moment shaped his lifelong mission to treat women with comprehensive, individualized care—not cookie-cutter patches or “blind firing” estrogen without context. In this episode, he explains: 🧬 Why FSH matters just as much as estrogen 🧠 How FSH affects metabolism, bone density, fat storage, and even Alzheimer’s risk 🩺 What truly responsible hormone therapy should look like 💬 And how we must challenge trends in medicine that ignore the full picture Citations: Mao L, Wang L, Bennett S, Xu J, Zou J. Effects of follicle-stimulating hormone on fat metabolism and cognitive impairment in women during menopause. Front Physiol. 2022 Dec 5;13:1043237. doi: 10.3389/fphys.2022.1043237. PMID: 36545281; PMCID: PMC9760686. Spicer J, Malaspina D, Blank SV, Goosens KA. Follicle-stimulating hormone: More than a marker for menopause: FSH as a frontier for women's mental health. Psychiatry Res. 2025 Mar;345:116239. doi: 10.1016/j.psychres.2024.116239. Epub 2024 Oct 28. PMID: 39892305; PMCID: PMC12094525. Sponton CH, Kajimura S. Burning Fat and Building Bone by FSH Blockade. Cell Metab. 2017 Aug 1;26(2):285-287. doi: 10.1016/j.cmet.2017.07.018. PMID: 28768167; PMCID: PMC9142816 Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy is the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-... -More Links- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com…

Dr. Brendan McCarthy

1
Why Perimenopausal Hormone Labs Do Matter — Debunking Dangerous Myths 30:27

לפני 25 weeks30:27

30:27

Welcome to the podcast with Dr. Brendan McCarthy! In this video, Dr. Brendan McCarthy breaks down common misconceptions about hormone testing and treatment during perimenopause — including why many influencers and physicians get it wrong. From the misuse of expensive boutique tests like the Dutch test, to the dangers of suppressive hormone therapies without proper lab monitoring, Dr. McCarthy explains the science behind hormone fluctuations, why labs do provide valuable insights, and the importance of individualized care. Learn why ignoring hormone labs isn’t just lazy — it’s harmful — and how true, affordable care should prioritize your unique hormonal balance, not profits. If you’re navigating perimenopause, this video offers critical clarity on your options and what you truly deserve from your healthcare provider. Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-... -More Links- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com…

Dr. Brendan McCarthy

1
Should You Get HRT Without Lab Work? Why I Always Test First 18:15

לפני 26 weeks18:15

18:15

Welcome to the podcast with Dr. Brendan McCarthy! Can you start hormone replacement therapy (HRT) or bioidentical hormones without lab testing? Technically—yes. But should you? In this episode, Dr. Brendan McCarthy, Chief Medical Officer of Protea Medical Center, shares his medical perspective on why skipping labs could put your health at risk. Responding to viral videos that suggest lab work is unnecessary, Dr. McCarthy walks you through: ✅ Why objective data matters—especially for hormone care ✅ The dangers of prescribing hormones without testing ✅ How HRT can be safely and affordably customized ✅ Real-life clinical scenarios that show the power of lab-guided treatment Whether you're navigating perimenopause, menopause, or curious about functional medicine, this episode aims to inform—not attack—and to elevate the standard of care all patients deserve. Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Citations: - O'Connell, Mary Beth. "Pharmacokinetic and pharmacologic variation between different estrogen products." The Journal of Clinical Pharmacology 35.9S (1995): 18S-24S.. - Qureshi, Rehana, et al. "The major pre-and postmenopausal estrogens play opposing roles in obesity-driven mammary inflammation and breast cancer development." Cell metabolism 31.6 (2020): 1154-1172.. - Bagot CN, Marsh MS, Whitehead M, Sherwood R, Roberts L, Patel RK, Arya R. The effect of estrone on thrombin generation may explain the different thrombotic risk between oral and transdermal hormone replacement therapy. J Thromb Haemost. 2010 Aug;8(8):1736-44. doi: 10.1111/j.1538-7836.2010.03953.x. Epub 2010 Jun 14. PMID: Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-... -More Links- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com…

Dr. Brendan McCarthy

1
Testosterone in Women: Dosing, Labs & What Most Doctors Miss 27:03

לפני 27 weeks27:03

27:03

Welcome to the podcast with Dr. Brendan McCarthy! This episode takes you deep into the real-world practice of prescribing testosterone therapy for women. This is not a high-level overview—this is a nuts and bolts breakdown: ✅ Who it's for ✅ How it's dosed ✅ What labs to run ✅ What delivery methods are safest ✅ Why it's often done wrong—and how to get it right With over 20 years of clinical experience, Dr. McCarthy shares the insights no seminar or textbook can offer, including the emotional and psychological challenges women face when beginning testosterone therapy, and the very real fears around side effects and community stigma. 📌 Whether you’re a patient looking for answers, or a clinician wanting to deepen your knowledge, this episode is for you. Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Citations: Popma, Arne, et al. "Cortisol moderates the relationship between testosterone and aggression in delinquent male adolescents." Biological psychiatry 61.3 (2007): 405-411 Likhtik, E., Stujenske, J. M., Topiwala, M. A., Harris, A. Z. & Gordon, J. A. Prefrontal entrainment of amygdala activity signals safety in learned fear and innate anxiety. Nat. Neurosci. 17, 106–113 (2014). Brannon, Skylar M., et al. "Exogenous testosterone increases sensitivity to moral norms in moral dilemma judgements." Nature Human Behaviour 3.8 (2019): 856-866.. M.H.M. Hutschemaekers, R.A. de Kleine, M.L. Davis, M. Kampman, J.A.J. Smits, K. Roelofs,Endogenous testosterone levels are predictive of symptom reduction with exposure therapy in social anxiety disorder,Psychoneuroendocrinology,Volume 115,2020,104612 Barel, E, Abu‐Shkara, R, Colodner, R, et al. Gonadal hormones modulate the HPA‐axis and the SNS in response to psychosocial stress. J Neuro Res. 2018; 96: 1388– 1397. https://doi.org/10.1002/jnr.24259 Buades-Rotger, M., Engelke, C., Beyer, F. et al. Endogenous testosterone is associated with lower amygdala reactivity to angry faces and reduced aggressive behavior in healthy young women. Sci Rep 6, 38538 (2016). https://doi.org/10.1038/srep38538 Ando, Sebastiano, et al. "Breast cancer: from estrogen to androgen receptor." Molecular and cellular endocrinology193.1-2 (2002): 121-128. Somboonporn, Woraluk, and Susan R. Davis. "Testosterone effects on the breast: implications for testosterone therapy for women." Endocrine reviews 25.3 (2004): 374-388. Donovitz, Gary, and Mandy Cotten. "Breast cancer incidence reduction in women treated with subcutaneous testosterone: testosterone therapy and breast cancer incidence study." European journal of breast health 17.2 (2021): 150. Glaser, Rebecca L., Anne E. York, and Constantine Dimitrakakis. "Incidence of invasive breast cancer in women treated with testosterone implants: a prospective 10-year cohort study." BMC cancer 19.1 (2019): 1271. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-... -More Links- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com…

Dr. Brendan McCarthy

1
The Truth About Testosterone in Women: What Your Doctor May Not Be Telling You 21:50

לפני 28 weeks21:50

21:50

Welcome to the podcast with Dr. Brendan McCarthy! In this episode we dive deep into one of the most misunderstood and debated topics in hormone health: testosterone replacement therapy (TRT) for women. You may have heard horror stories—or glowing reviews. But what’s the truth? Dr. McCarthy discusses: - Why testosterone matters for women’s health - How it affects brain chemistry, mood, bone density, and even breast tissue - Its role after estrogen-suppressing breast cancer treatments - The difference between safe and unsafe TRT - What your provider should be doing to monitor and manage it effectively Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Citations: Popma, Arne, et al. "Cortisol moderates the relationship between testosterone and aggression in delinquent male adolescents." Biological psychiatry 61.3 (2007): 405-411 Likhtik, E., Stujenske, J. M., Topiwala, M. A., Harris, A. Z. & Gordon, J. A. Prefrontal entrainment of amygdala activity signals safety in learned fear and innate anxiety. Nat. Neurosci. 17, 106–113 (2014). Brannon, Skylar M., et al. "Exogenous testosterone increases sensitivity to moral norms in moral dilemma judgements." Nature Human Behaviour 3.8 (2019): 856-866.. * M.H.M. Hutschemaekers, R.A. de Kleine, M.L. Davis, M. Kampman, J.A.J. Smits, K. Roelofs,Endogenous testosterone levels are predictive of symptom reduction with exposure therapy in social anxiety disorder,Psychoneuroendocrinology,Volume 115,2020,104612 Barel, E, Abu‐Shkara, R, Colodner, R, et al. Gonadal hormones modulate the HPA‐axis and the SNS in response to psychosocial stress. J Neuro Res. 2018; 96: 1388– 1397. https://doi.org/10.1002/jnr.24259 * Buades-Rotger, M., Engelke, C., Beyer, F. et al. Endogenous testosterone is associated with lower amygdala reactivity to angry faces and reduced aggressive behavior in healthy young women. Sci Rep 6, 38538 (2016). https://doi.org/10.1038/srep38538 Ando, Sebastiano, et al. "Breast cancer: from estrogen to androgen receptor." Molecular and cellular endocrinology193.1-2 (2002): 121-128. Somboonporn, Woraluk, and Susan R. Davis. "Testosterone effects on the breast: implications for testosterone therapy for women." Endocrine reviews 25.3 (2004): 374-388. Donovitz, Gary, and Mandy Cotten. "Breast cancer incidence reduction in women treated with subcutaneous testosterone: testosterone therapy and breast cancer incidence study." European journal of breast health 17.2 (2021): 150. Glaser, Rebecca L., Anne E. York, and Constantine Dimitrakakis. "Incidence of invasive breast cancer in women treated with testosterone implants: a prospective 10-year cohort study." BMC cancer 19.1 (2019): 1271. Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-... -More Links- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com…

Dr. Brendan McCarthy

1
Testosterone Therapy for Women: Breaking the Stigma 17:38

לפני 29 weeks17:38

17:38

Welcome to the podcast with Dr. Brendan McCarthy! Today’s episode is all about testosterone therapy in women—a topic that’s often misunderstood, highly debated, and rarely taught in depth. I’m sharing what I’ve learned over my years of clinical experience, how I approach testosterone use in women safely, and why the conversation around it needs to evolve. Dr. Brendan McCarthy founded Protea Medical Center in 2002. While he’s been the chief medical officer, Protea has grown and evolved into a dynamic medical center serving the Valley and Central Arizona. A nationally recognized as an expert in hormone replacement therapy, Dr McCarthy s the only instructor in the nation who teaches BioHRT on live patients. Physicians travel to Arizona to take his course and integrate it into their own practices. Besides hormone replacement therapy, Dr. McCarthy has spoken nationally and locally before physicians on topics such as weight loss, infertility, nutritional therapy and more. Hurst BS, Jones AI, Elliot M, Marshburn PB, Matthews ML. Absorption of vaginal estrogen cream during sexual intercourse: a prospective, randomized, controlled trial. J Reprod Med. 2008;53(1):29–32. PMID: 18251358 Thank you for tuning in and don't forget to hit that SUBSCRIBE button! Let us know in the COMMENTS if you have any questions or what you may want Dr. McCarthy to talk about next! Check out Dr. Brendan McCarthy's Book! https://www.amazon.com/Jump-Off-Mood-... -More Links- Instagram: www.instagram.com/drbrendanmccarthy TikTok: www.tiktok.com/drbrendanmccarthy Clinic Website: www.protealife.com…

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