Got Guts: Small Intestine Neuroendocrine Tumor: Its cell-of-origin has a curious fate of tumorigenesis

American Journal of Physiology-Gastrointestinal and Liver Physiology Podcast

Take a listen to our latest podcast with coauthor Dr. Yoshi Sei as he discusses the recently published manuscript "Tissue- and cell-specific properties of enterochromaffin cells affect the fate of tumorigenesis toward nonendocrine adenocarcinoma of the small intestine" with Editor in Chief Professor Mark Frey. Small intestinal neuroendocrine tumors are of putative enterochromaffin (EC) cell origin and are the most common malignancy in the small intestine, followed by adenocarcinoma. Dr Sei, explains how tissue- and cell-specific properties of EC cells such as cell turnover, migration, and dedifferentiation, affect their fate of tumorigenesis.

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