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תוכן מסופק על ידי StemCells@Lunch Digested. כל תוכן הפודקאסטים כולל פרקים, גרפיקה ותיאורי פודקאסטים מועלים ומסופקים ישירות על ידי StemCells@Lunch Digested או שותף פלטפורמת הפודקאסט שלהם. אם אתה מאמין שמישהו משתמש ביצירה שלך המוגנת בזכויות יוצרים ללא רשותך, אתה יכול לעקוב אחר התהליך המתואר כאן https://he.player.fm/legal.
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This Is Woman's Work with Nicole Kalil


1 The Icelandic Art of Intuition with Hrund Gunnsteinsdóttir | 307 35:19
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We’ve turned intuition into a buzzword—flattened it into a slogan, a gut feeling, or a vague whisper we don’t always know how to hear. But what if intuition is so much more? What if it's one of the most powerful tools we have—and we’ve just forgotten how to use it? In this episode, I’m joined by Hrund Gunnsteinsdóttir , Icelandic thought leader, filmmaker, and author of InnSæi: Icelandic Wisdom for Turbulent Times . Hrund has spent over 20 years studying and teaching the science and art of intuition through her TED Talk, Netflix documentary ( InnSæi: The Power of Intuition ), and global work on leadership, innovation, and inner knowing. Together, we explore what intuition really is (hint: not woo-woo), how to cultivate it in a culture obsessed with logic and overthinking, and why your ability to listen to yourself might be the most essential skill you can develop. In This Episode, We Cover: ✅ Why we’ve misunderstood intuition—and how to reclaim it ✅ Practical ways to strengthen your intuitive muscle ✅ What Icelandic wisdom teaches us about inner knowing ✅ How to use intuition during uncertainty and decision-making ✅ Why trusting yourself is an act of rebellion (and power) Intuition isn’t magic—it’s a deep, internal guidance system that already exists inside you. The question is: are you listening? Connect with Hrund: Website: www.hrundgunnsteinsdottir.com TedTalk: https://www.ted.com/talks/hrund_gunnsteinsdottir_listen_to_your_intuition_it_can_help_you_navigate_the_future?utm_campaign=tedspread&utm_medium=referral&utm_source=tedcomshare Newsletter: https://hrundgunnsteinsdottir.com/blog/ LI: www.linkedin.com/in/hrundgunnsteinsdottir IG: https://www.instagram.com/hrundgunnsteinsdottir/ Book: InnSæi: Icelandic Wisdom for Turbulent Times Related Podcast Episodes: How To Breathe: Breathwork, Intuition and Flow State with Francesca Sipma | 267 VI4P - Know Who You Are (Chapter 4) Gentleness: Cultivating Compassion for Yourself and Others with Courtney Carver | 282 Share the Love: If you found this episode insightful, please share it with a friend, tag us on social media, and leave a review on your favorite podcast platform! 🔗 Subscribe & Review: Apple Podcasts | Spotify | Amazon Music…
Episode 121 - Prof Kevin Eggan - "Science progresses through replication, validation, extension"
Manage episode 274996400 series 1291709
תוכן מסופק על ידי StemCells@Lunch Digested. כל תוכן הפודקאסטים כולל פרקים, גרפיקה ותיאורי פודקאסטים מועלים ומסופקים ישירות על ידי StemCells@Lunch Digested או שותף פלטפורמת הפודקאסט שלהם. אם אתה מאמין שמישהו משתמש ביצירה שלך המוגנת בזכויות יוצרים ללא רשותך, אתה יכול לעקוב אחר התהליך המתואר כאן https://he.player.fm/legal.
Today, Professor Kevin Eggan from the Department of Stem Cell and Regenerative Biology at Harvard University, is interviewed by PhD student Peter Harley. Kevin talks about the difficulties of studying neurodegenerative disorders and applying stem cell technologies to study motor neuron disease/ALS. He discusses why highlighting and understanding contradictory findings is an essential part of scientific research and the reliability of using mouse models to study ALS. To find out more about Kevin’s work please visit the following website: https://hsci.harvard.edu/people/kevin-c-eggan-phd
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156 פרקים
Manage episode 274996400 series 1291709
תוכן מסופק על ידי StemCells@Lunch Digested. כל תוכן הפודקאסטים כולל פרקים, גרפיקה ותיאורי פודקאסטים מועלים ומסופקים ישירות על ידי StemCells@Lunch Digested או שותף פלטפורמת הפודקאסט שלהם. אם אתה מאמין שמישהו משתמש ביצירה שלך המוגנת בזכויות יוצרים ללא רשותך, אתה יכול לעקוב אחר התהליך המתואר כאן https://he.player.fm/legal.
Today, Professor Kevin Eggan from the Department of Stem Cell and Regenerative Biology at Harvard University, is interviewed by PhD student Peter Harley. Kevin talks about the difficulties of studying neurodegenerative disorders and applying stem cell technologies to study motor neuron disease/ALS. He discusses why highlighting and understanding contradictory findings is an essential part of scientific research and the reliability of using mouse models to study ALS. To find out more about Kevin’s work please visit the following website: https://hsci.harvard.edu/people/kevin-c-eggan-phd
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156 פרקים
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StemCells@Lunch Digested

1 Episode 153: Dr Ina Sonnen "It is possible to have a career and a family in science" 24:43
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In this episode, Ina Sonnen, a researcher at the Hubrecht Institute in the Netherlands, is interviewed by Postdocoral researcher JF Darrigrand. Ina explains which are the big questions studied in her lab, notably how cells can communicate not only via the nature of signals they exchange but also through the dynamics of these signlas. She shares how advances in microscopy, microfluidics and cell culture are helping researchers to make more and more discoveries. Having recently founded her lab, she tells us more about what she found was either challenging or rewarding in her new role. Lastly, she insists on why she thinks being a scientist is a good job when you want to start a family. To find out more about Ina's research, check out the following links: https://www.sonnenlab.org…
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1 Episode 152: Prof Andrew Ewald "Understand the simple rules generating apparent complexity" 23:34
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In today’s episode, Prof. Andrew Ewald, Director of the Cell Biology Department at the Johns Hopkins School of Medicine is interviewed by Inês Tomás. Prof Ewald explains how he transitionned from a background in physics to the field of cancer biology. He touches upon why cancer is such a specific type of disease, how cancer cells talk to each other during metastasis, and how their interaction with immune cells is crucial for disease development. Prof Ewald also discusses the evolution of the tools available for cancer biologists and how the emergence of new technologies are changing the field. Lastly, he shares some inspiring mentoring advice on how to reach an interdisciplinary and rewarding career.…
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1 Episode 151: Dr William Roman "Use your PhD as a platform" 16:38
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In today’s episode, Dr. William Roman, a research associate at Stanford University, is interviewed by Dr. Davide Danovi. William explains how he is combining live cell imaging and quantitative approaches to answer fundamental questions in muscle biology. He shares some inspiring mentoring advice on how to let students use their PhDs as platforms to express themselves throught their science and discover what type of science they like, both in terms of subject and technique.…
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1 Episode 150: Prof Shalev Itzkovitz "We can infer the design principles of organs" 29:23
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In today’s episode, Shalev Itzkovitz, a professor at the Weizman Institute, Israel, is interviewed by Postdocoral researcher Georgina Goss. Shalev shares the discoveries of his lab on the design principles that shape and maintain metabolic organs such as the intestine and the liver. He explains the very advanced techniques used in modern biology, and more specifically in his lab, to address such fundamental questions. Having started his education in mechanical engineering, he discusses what motivated him to transition to the resolution of biological questions and how resolving these questions is somewhat similar to retro-engineering. Lastly, he touches upon what fascinates him in studying the biology of metabolic organs. To find out more about Shalev's research, check out the following links: https://shalevlab.weizmann.ac.il…
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1 Episode 149: Professor Xin Chen-“We are very fascinated by this kind of ‘immortality’ of germ cells” 15:53
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In today’s episode, Prof Xin Chen, a group leader at Johns Hopkins University in Baltimore, is interviewed by PhD student Daria Belokhvostova. Xin takes us into the world of germline stem cell epigenetics and how its regulation can influence the ability of these cells to divide asymmetrically. She shares her passion for the biology of germ cells and explains why the fruit fly Drosophila is such a good system for her studies. Xin talks about how scientific collaborations are helping to expand her findings to different biological systems. Finally, she tells us about the challenges of keeping the lab running through pandemic times and the joy of seeing in-person interactions come back. To find out more about Xin’s research, check out the following link: https://bio.jhu.edu/directory/xin-chen/…
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1 Episode 148: Dr Allison Bardin- “Unexpected results lead to novel discoveries” 15:57
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In today’s episode, Dr Allison Bardin, a group leader at Institut Curie, is interviewed by PhD student Vassia Salameti. Allison talks about how she got interested in asymmetric cell division while working on budding yeast, followed by her work on fly as a postdoc that derived her into the field to study cell fate acquisitions and stem cell biology. She shared the details about how Drosophila is excellent model to study various genetic alterations and cost effective. Allison further emphasised on the importance of fundamental research and how that could lead to interesting discoveries that could be further translated into clinics. Finally, she talks about importance of collaboration as well as importing expertise in lab along with some interesting advice for PhDs who plan to pursue academic career. To find out more about Allison's research, check out the following link: https://science.institut-curie.org/research/biology-cancer-genetics-and-epigenetics/developmental-biology-and-genetics/team-bardin/…
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1 Episode 147: Professor Yukiko Yamashita- “Junk DNA may not be all Junk” 16:27
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In today’s episode, Prof Yukiko Yamashita, a group leader at Whitehead Institute for Biomedical Research, MIT, is interviewed by PhD student Joshua Reeves. Yukiko talks about how her lab got interested in understanding the possible mechanism of non siter chromatid segregation in germline cells. She talks about how they started looking at the interesting mechanisms regulating the immortality of germlines cells in Drosophila. Yukiko also shares her opinion regarding Junk DNA and how it might not all be junk like noncoding RNAs. Lastly, she shares her advice to be learner for rest of life and get used to stepping outside comfort zone. And to become comfortable not being expert all the time. To find out more about Yukiko’s research, check out the following link: https://yamashitalab.wi.mit.edu/…
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1 Episode 146: Prof Ludo Van Den Bosch– “Exciting time for researchers” 14:32
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In today’s episode, Prof Ludo Van Den Bosch a group leader at VIB-KU Leuven Center for Brain & Disease Research, is interviewed by PhD student Abigail Isaacson. Ludo talks about his labs goal and how they use different model systems to understand disease as good as possible with goal to develop therapies. He also highlighted the importance of using different models from fruit fly, zebrafish to mice depending on context and questions. Ludo also emphasized about obstacles in managing ALS along with advancement in past 25yrs and how iPSCs have made big difference and given new insights for understanding diseases. Ludo shared his experience as being a scientist and how much he enjoy interaction with young people and other fellow colleagues. To find out more about Ludo's research, check out the following link: https://cbd.vib.be/labs/van-den-bosch-lab…
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1 Episode 145: Prof Elena Ezhkova- “The more you try understand science the more interesting it gets” 15:39
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In today’s episode, Prof Elena Ezhkova, a group leader at Icahn School of Medicine, is interviewed by PhD student Vassia Salameti. Elena talks about the potential of stem cells in therapy and how her interest developed towards understanding the role of epigenetic regulators in stem cell reprogramming. She shares about how companies are getting interested in small molecular drugs that target epigenetic regulators which could be used as personalized therapy. Elena also emphasizes the importance of clinical collaboration and highlights how important it is to get the inputs from clinicians at the beginning of project to get better understanding of the disease. Lastly, she shares her advice for PhDs to find the research direction of interest and not be afraid things will work out!!! To find out more about Elena's research, check out the following link: https://www.ezhkova-lab.com/…
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1 Episode 144- Prof Filipe Pereira- "It's about defining what will keep you fueled for years" 19:07
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In today’s episode, Prof Filipe Pereira, a professor at Lund University, Sweden, is interviewed by postdocoral researcher Jean-Francois Darrigrand. Filipe shares how he started his career in the fields of stem cells reprogramming and immunotherapy, as well as his experience working in the US and different european countries. Filipe also discusses about how he balances his activities of leader of an academic group and of a biotech company. Lastly, he explains why mentoring is a fantastic source of motivation for him. To find out more about Filipe's research, check out the following link: https://pereiralab.com/team/carlos-filipe-pereira/…
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1 Episode 143 -Prof Denis Duboule - "As long as people are happy in your lab, it's fine" 14:38
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In today’s episode, Prof Denis Duboule, a professor of developmental biology at EPFL and Univeristy of Geneva is interviewed by PhD student Abigail Isaacson. Denis talks about how his first interest for mushrooms initiated his whole career in biology. He shares with us his fascination for the encoding of time in the genome, which ensures the proper development of embryos. Denis also talks about how priotities change during the life of a laboratory head, shifting from publishing to seeing your lab members grow and succeed on their own. To find out more about Denis' research, check out the following link: https://genev.unige.ch/research/laboratory/Denis-Duboule…
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1 Episode 142 -Prof Dagmar Iber- "Don't play too safe and be lucky." 11:05
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In today’s episode, Prof Dagmar Iber, a professor at ETH, Zurich, is interviewed by PhD student Vasiliki Salameti. Dagmar talks about the similarity between investment banking and academia . She describes her interest in modelling organogenesis and patterning systems. She discusses the importance of collaboration. She also advised students to take risk and initiative to try to do things they want to. As a university professor, she shared how she enjoyed the scientific journey in finding things out, but also teaching and seeing students grow. To find out more about Dagmar's research, check out the following links: https://www.bsse.ethz.ch/cobi https://bsse.ethz.ch/cobi/group/people/person-detail.MTQ5NDI0.TGlzdC8yMjA0LC0xMDM3ODQxNDk3.html…
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1 Episode 141 - Dr Vikas Trivedi - “You get to learn things from people that you would not know” 18:47
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In today’s episode, Dr Vikas Trivedi, a group leader at EMBL Barcelona, is interviewed by PhD student Prudence Lui. Vikas talks about his scientific journey and his research on using embryonic organoids to study self-organisation of cells. He describes the challenge in this field to use interdisciplinary approaches to study complex biological phenomena. He discusses the benefits of developing broad multidisciplinary expertise at the lab. As a group leader in science, he finds problem solving, working with intelligent people and contributing to other people’s career very rewarding. We also get to learn about Vikas’s interests beyond the lab. To find out more about Vikas's research, check out the following link: https://www.embl.org/groups/trivedi/…
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1 Episode 140- Dr Emma Rawlins "I'll look at stem cell in any systems" 21:49
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In today’s episode, Dr Emma Rawlins, a senior group leader at the Gurdon Institute in University of Cambridge. She is interviewed by PhD student Elena Drudi. Emma talks about her research on stem cells in mammalian lungs using both mouse and human organoid models. She discusses the pros and cons of the two models. She describes her research interest in understanding normal embryonic lung development, with the aim to further repurpose these cues for lung repair/regeneration in adults. She emphasises how functional human genetics on a population level, in combination with human organoids models, can further help dissecting diseases susceptibility and regeneration. She also shares her journey from studying drosophila to human lung biology, and how going aboard no longer seems to be a necessity to continue one's career. To learn more about Emma’s recent postdoc work, check out the following links: https://www.gurdon.cam.ac.uk/research/rawlins…
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1 Episode 139 - Dr Vanessa Ribes - “We make bonds in thinking and developing ideas” 18:49
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In today’s episode, Dr Vanessa Ribes, a group leader at Jacques Monod Institute, Paris, is interviewed by PhD student Victoria Tsang. Vanessa talks about her research on embryonic development of the spinal cord, its transcriptional regulation, the pathology of related congenital diseases, as well as cancers. She describes her long-time passion for biology and how she went from marine biology to agriculture to her current research. She discusses how meeting patients motivated and influenced her work. She shares her favourite aspects of being a scientist and her future focuses. She emphasises the importance of pleasure in pursuing a scientific career. To find out more about Vanessa's research, check out the following link: https://www.ijm.fr/en/864/research-groups/transcriptional-networks.htm…
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1 Episode 138 - Dr Carla Mulas - "Beyond mapping cell states and identities" 11:28
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In today’s episode, Dr Carla Mulas, a postdoc in Stem Cell Institue at Cambridge University, is interviewed by PhD student Haneen Alsehi. Carla talks about her amazing research using biophysics to understand cell state transition. She discusses her journey in transiting from a biochemistry background to studying stem cells and their fate commitment, and her keen interest in how stem cells change their properties during differentiation. She talks about the challenge of the current cell state transition field in the need to go beyond mapping cell states and cell identities. She also shares her career insights in identifying what one wants to learn and the necessity of a good mentor. To find out more about Kristina's research, check out the following link: https://sites.google.com/view/cmulasresearch…
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1 Episode 137 - Dr Kristina Haase - "These vessel systems are so beautiful!" 14:20
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In today’s episode, Dr Kristina Haase, a group leader at EMBL Barcelona, is interviewed by PhD student Prudence Lui. Kristina talks about her amazing research on bioengineered vascular networks and what kept her motivated to work on this for years. She discusses some challenges to be considered when generating advanced vascularised experiment models. She shares her fruitful experience of doing research across continents and in different areas. She emphasises the importance of having a clear biological question when doing science. We will also learn something about Kristina outside of the lab! To find out more about Kristina's research, check out the following link: https://www.embl.es/research/unit/haase/index.html…
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1 Episode 136 - Dr. Dominika Dziedzicka- "Differentiation propensity" 17:28
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On today’s episode, Dr Dominika Dziedzicka, a postdoc working with Prof Ludovic Vallier from MRC Cambridge Stem Cell Institute. She is interviewed by Daria Belokhvostova, a PhD student in Centre of Stem Cells & Regenerative Medicine in King’s College London. Dominika talks about her PhD and recent postdoc work on human embryonic and induced pluripotent stem cells. She discusses the differences between differentiation propensity and differentiation potential of stem cells. To learn more about Dominika’s recent postdoc work, check out the following links: https://www.stemcells.cam.ac.uk/people/pi/vallier…
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1 Episode 135 - Ieva Berzanskyte - "When I started understanding it more I grew fond of it." 17:41
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In today’s episode, Ieva Berzanskyte, our own graduating PhD student at the Centre for Stem Cells and Regenerative Medicine at King’s College London, is interviewed by PhD student Inês Tomás. Ieva talks about her exciting work on growing stem cells from patient tissues, then turning them into neurons to find a cure for spinal cord injury. She shares her thoughts on how the neuroscience field can speed up the discovery and translation of therapies into clinics. Following her deep interest in advancing biotechnologies, she discusses her upcoming post-doctoral research on the direct conversion between different cell types and its application. To find out more about Ieva’s experience check out the following link: https://www.regenerativemedicinephd.co.uk/student-profiles/ieva-berzanskyte…
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1 Episode 134-Prof Michael Levin-"Learn the best and put them together in your own way" 14:44
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On today’s episode, Prof Michael Levin, a renowned regenerative and developmental biologist of Tufts University and Wyss Institute at Harvard University, is interviewed by Dr Davide Danovi, a group leader in Centre of Stem Cells & Regenerative Medicine in King’s College London. Mike talks about his multi-disciplinary work in decoding bioelectrical signals of cells, in particularly how information is stored, processed and used for functions within the biological system. He discusses how this biological knowledge can give rise to applications in machine learning and artificial intelligence. He also shares his view on ways to communicate across different disciplines, and how to be equipped for a multi-disciplinary mindset and skillsets. To learn more about Mike’s work, check out the following links: https://wyss.harvard.edu/team/associate-faculty/michael-levin-ph-d/ and https://ase.tufts.edu/biology/labs/levin…
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1 Episode 133 – Ana Pombo – “Every day I learn something.” 18:01
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In today’s episode, Prof Ana Pombo, group leader at the Max Delbrück Center for Molecular Medicine in Berlin, is interviewed by PhD student Vasiliki Salameti. Ana talks about her pioneering work that enabled scientists to dissect how the genome is packaged inside cells and how this method is evolving with new single-cell technologies. She shares her view on future technology development which should help us make predictions. She discusses collaboration in science and the importance of timing in making research decisions. To learn more about Ana’s work check out the following link: https://www.mdc-berlin.de/pombo…
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1 Episode 132 – Nicolas Rivron – “By understanding the embyro, you understand regeneration.” 20:16
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On today’s episode, Dr Nicolas Rivron, group leader at the Institute of Molecular Biotechnology, Austrian Academy of Science, is interviewed by PhD student Sergi Junyent Espinosa. Nicolas discusses his research building stem-cell based embryo models. He talks about the self-organising nature of tissue development in the embryo and how this can help us understand key principles of regeneration. For more information on Nicolas’ work check out the following link: https://www.oeaw.ac.at/imba/research/nicolas-rivron…
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1 Episode 131 - Vivian Li - “I felt like the intestine is actually quite a beautiful system.” 18:38
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On today’s episode, Dr Vivian Li, group leader of the Stem Cell and Cancer Laboratory at the Francis Crick Institute, is interviewed by PhD student Elena Drudi. Vivian talks about her background in plant biotechnology, colon cancer research and working in Hans Clevers lab and her current research focus using human gut organoids to ask how stem cells are maintained in healthy guts, what happens when it goes wrong, and the Wnt signalling pathway’s role in this. She also talks about the future of engineering parts of the bowel to replace damaged and missing bowel. For more information on Vivian’s work check out the following link: https://www.crick.ac.uk/research/labs/vivian-li…
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1 Episode 130 - Derk Ten Berge - "It does require some bravery to spend the time to look for that" 16:58
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In today’s episode, Dr Derk ten Berge, an Associate Professor in the department of Cell Biology at Erasmus MC University Medical Center Rotterdam, is interviewed by PhD student Daria Belokhvostova. Derk discusses his research on embryonic development and pluritpotency (the ability of a stem cell to make all the cells of the embryo) and the mechanisms of how cells become pluripotent. He talks about an intermediate stage of embryonic development called rosette stem cells. He considers about how his lab is dealing with the impact of Covid.…
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1 Episode 129 - Ana-Maria Cujba - "I think my passion is for organoids." 14:16
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Ana-Maria Cujba, a PhD student at the Centre for Stem Cell's and Regenerative Medicine at King's College London, is interviewed by PhD student Ella Hubber. Ana-Maria discusses her work using human induced pluripotent stem cells and pancreatic organoids to study a new mechanism in mature onset diabetes of the young (MODY). She dives into the development of pancreatic organoids and making a more physiologically relevant system. She also discusses publishing her work as a PhD student and transitioning from a PhD to a post-doc. To learn more about Ana-Maria's work, check out the following links: https://www.regenerativemedicinephd.co.uk/student-profiles/ana-maria-cujba https://orcid.org/0000-0003-3917-6751…
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1 Episode 128 - Prof Muzlifah Haniffa - "We are going to map the 37 trillion cells in the human body." 12:56
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Professor Muzlifah Haniffa, Professor of Dermatology and Immunology at Newcastle University, is interviewed by researcher Dr Clarisse Ganier. Muzz talks about her pioneering work in the fields of dermatology, immunology and genomics. She discusses her involvement in the human cell atlas, that aims to map all the cells of the human body. Muzz also speaks about the importance of public engagement in research science. To learn more about Muzz's work visit the following link: https://www.ncl.ac.uk/medical-sciences/people/profile/mahaniffa.html…
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1 Episode 127- Prof Francesco Saverio Tedesco - “Seeing patients gives you the right motivation.” 15:48
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Prof Francesco Saverio Tedesco, Professor of Neuromuscular Biology and Regenerative Medicine at University College London, is interviewed by researcher Dr Davide Danovi. Francesco talks about his work using stem cells to understand and develop new therapies for muscular diseases such as muscular dystrophy. He speaks about the balance between his professions as a clinician and a scientist, and how this supports the translational goal of his research. To learn more about Francesco 's work visit the following link: https://www.ucl.ac.uk/biosciences/people/saverio-tedesco P.S. check out our new logo, designed by PhD student Matt Chung!…
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1 Episode 126 - Dr Madeline Lancaster - "It was a classic story of scientific serendipity" 12:48
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Dr Madeline Lancaster, Group Leader at the Cell Biology Division of the MRC Laboratory of Molecular Biology in Cambridge, is interviewed by PhD student Ella Hubber. Madeline talks about the chance discovery and ongoing development of cerebral organoids and their use in studying human brain development and size differences between human and non-human apes. She also touches on the importance of engaging with the public as a scientist. To learn more about Madeline's work visit the following link: https://www2.mrc-lmb.cam.ac.uk/groups/lancaster/…
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1 Episode 125 - Dr Jürgen Knoblich- “Studying the brain is like studying oneself.” 20:57
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On today’s episode, Dr Jürgen Knoblich, scientific director at the Institute of Molecular Biology at the Austrian Academy of Sciences, is interviewd by PhD student Sergi Junyen. Jürgen talks about his research journey to studying brains, the benefits of using fruit flies (Drosophila) in research, and the development and future of cerebral organoids, including their use in genetic screening. To find out more about Jürgen’s research follow this link: https://www.imba.oeaw.ac.at/research/juergen-knoblich/team/…
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1 Episode 125 - Dr Randolph Ashton - "I have faith in the cells, they can do a lot themselves." 11:53
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Randolph Ashton, Associate Professor of Biomedical Engineering at University of Wisconsin-Madison, is interviewed by PhD student Ieva Berzanskyte. Randolph discusses his research engineering novel materials and methodologies to direct stem cell behaviour in a reproducible and scalable manner. He talks about how harnessing the natural ability of cells to differentiate can be used to develop models and scaffolds for regenerative medicine. To find out more about Randolph’s work please visit the following website: https://directory.engr.wisc.edu/bme/Faculty/Ashton_Randolph/…
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1 Episode 109 - Prof James Sharpe - "You were limited by nothing but your own imagination." 13:22
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We return this week with an episode recorded during lockdown. Prof. James Sharpe, the head of EMBL Barcelona, is interviewed by PhD student Sergi Junyent. Prof. Sharpe is one of the key opinion leaders in developmental biology and bioengineering. Here, he talks about the pioneering work done by his group in understanding tissue development and discusses his how his work brings together his passion for computer programming and biology. For more information on Prof. Sharpe's research follow this link: https://www.embl.es/research/unit/sharpe/members/index.php?s_personId=CP-60027035…
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1 Episode 108 - Prof Jianping Fu - “Human development itself is just fascinating.” 18:06
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“Even just to understand the genesis of human being itself... It must be one of the holy grails of modern biology.” We return this week with an episode recorded during lockdown. Professor Jianping Fu, a professor of Mechanical Engineering, Biomedical engineering and Cell and Developmental Biology at the University of Michigan, is interviewed by PhD student Sergi Junyent. He talks about the technical difficulties and ethical issues of studying human development. He discusses the growing field of stem cell based embryo models to study the early stages of development and the future directions of these models. For more information on Jianping's research follow this link: http://me-web.engin.umich.edu/ibbl/…
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1 Episode 107 - Prof Ludovic Vallier - "The drive is to generate more knowledge." 17:41
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We return this week with an episode recorded during lockdown. Professor Ludovic Vallier, Professor of Regenerative Medicine within the Department of Surgery at Cambridge University and director of the National Institute for Health Research (NIHR) Cambridge Biomedical Research Centre hIPSCs (human induced pluripotent stem cells) core facility, is interviewed by PhD student Alice Vickers. He talks about his work using human pluripotent cells to generate pancreas, lung, gut and liver cells. He speaks about how his involvement in industry aims to generate cell types for clinical studies and for cell based therapy. For more information on Ludovic's research follow this link: https://www.stemcells.cam.ac.uk/People/pi/vallier…
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1 Episode 106 - Professor Peter Jones - "I think all scientists are curious by nature." 11:21
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We return this week with an episode recorded during lockdown. Professor Peter Jones, Professor of Endocrine Biology and head of the Department of Physiology at King's College London, is interviewed by PhD student Prudence Lui. Peter breaks down the basics of type 1 and type 2 diabetes and discusses his lab's recent research into the phenomenon of mitochondrial transfer. After 36 years at King's, Peter talks about what has kept him in scientific research. For more information on Peter's research follow this link: https://www.kcl.ac.uk/people/peter-jones…
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1 Episode 105-Dr Norah Fogarty-"Understanding the placenta we may treat disease before manifestation" 12:24
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We return this week to an episode recorded during lockdown. Dr Norah Fogarty, a new group leader at the Centre for Stem Cells and Regenerative Medicine at King's College London, is interviewed by PhD student Geraldine Jowett. Norah discusses her work on the development of the trophectoderm in the human embryo, which is the progenitor of early placental cells. She talks about how this work aims to further our understanding of human embryo development and early pregnancy loss, and may in the future lead to advances in assisted reproductive treatments. For more information on Norah's research follow this link: https://kclpure.kcl.ac.uk/portal/norah.fogarty.html…
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1 Episode 104 - Dr Alejo Rodriguez-Fraticelli - “What’s important is keeping an open mind.” 14:30
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Today on the SC@L Digested Podcast, Post-doc Miguel Bernabe-Rubio speaks with Alejo Rodriguez-Fraticelli, a research fellow at the Boston Children’s Hospital and soon-to-be principal investigator at the Institute for Research in Biomedicine in Barcelona. Alejo talks about his work using single cell maps to understand highly variable populations of cells and his future research focus on acute myeloid leukaemia. He also talks about developing his skills in computational biology through collaboration and the importance of stepping out of your comfort zone to succeed in interdisciplinary research. To see more of Alejo's research, follow this link: https://connects.catalyst.harvard.edu/Profiles/display/Person/176343…
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1 Episode 103 - Dr Victor Negri - A Lockdown Story 19:41
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“Take care of yourself, but also be aware of others who are more vulnerable than you” For this episode of SC@L digested, CSCRM public engagement officer Jessica Sells chatted with Victor Negri, A Post Doc in Fiona Watt’s lab, about his experience of lockdown. We've been exploring the impact that lockdown is having on our researchers by asking them to share their experiences. All of our staff are in unique positions, meaning lockdown is affecting their personal and work lives dramatically differently. For Victor the pandemic has been quite scary, as he has to take daily immunosuppressants for a health condition. He tells us how this has made him feel, and also his thoughts on how this situation will hopefully make the public take science more seriously... For more examples of our lockdown stories, visit the Watt Lab Blog here: www.wattlab.org…
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1 Episode 102- Geraldine Jowett- "There's something valuable about coming together and sharing values" 20:57
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We return this week to an episode recorded during lockdown. Geraldine Jowett, a final year PhD student on the Wellcome Trust Cell Therapies and Regenerative Medicine programme at King's College London, is interviewed by PhD student Emily Read. Geraldine discusses her work that uses stem cells to make mini-intestine in a dish models, also known as organoids, to understand Inflammatory Bowel Disease. She talks about the difficulties of an interdisciplinary PhD and what she has learnt moving between Germany, the United States and Britain. For more information on Geraldine's research follow this link: https://www.kcl.ac.uk/people/geraldine-jowett…
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1 Episode 101 - Dr José Silva - "It is the basic research that leads to applied science." 17:27
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We return this week to another interview recorded before lockdown. PhD student Christopher Lambert interviews Dr José Silva, a group leader at the Welcome-MRC Cambridge Stem Cell Institute. Dr Silva tells us about his career path from PhD to group leader and his current research in cellular reprogramming. They discuss the importance of collaboration in basic research and the need for a long-term, step-wise approach to progress the field of cellular reprogramming. Dr Silva also looks to the future, talking about his move into creating synthetic embryos. For more information about Dr Silva's research, follow this link: https://www.stemcells.cam.ac.uk/People/pi/silva…
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1 Episode 100 - Professor Fiona Watt - A Lockdown Story 17:33
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For our 100th SC@L episode, we've done something a bit different... We've been exploring the impact that lockdown is having on our researchers by asking them to share their experiences. All of our staff are in unique positions, meaning lockdown is affecting their personal and work lives dramatically differently . For this Lockdown Story, Public Engagement Officer Jess Sells remotely interviews CSCRM Director and MRC Exec Chair Professor Fiona Watt. Fiona talks about how she has been maintaining a work-life balance, thoughts on how this situation will change science, and society in general. For more examples of our lockdown stories, visit the Watt Lab Blog here: https://www.wattlab.org…
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1 Episode 99- Prof Susan Kimber- "Having stamina is probably more important than having brains" 17:52
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We return this week to another interview recorded before lockdown. Professor Susan Kimber, Professor of Stem & Developmental Biology at University of Manchester, speaks to PhD student Peter Harley. She discusses her work that uses human stem cell models to understand human development and to model vascular, skeletal and kidney diseases in a dish. She talks about how human stem cell models are important for both basic and translational science. When asked what makes a successful scientific career, she discusses the important of stamina and resilience. For more information on Professor Kimber's research follow this link: https://www.research.manchester.ac.uk/portal/sue.kimber.html…
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On this episode of the SC@L Digested Podcast, we return to an interview recorded before lockdown. PhD student, Inchul Cho, speaks to Dr Nathan Hawkshaw, a research associate in the Division of Musculoskeletal & Dermatological Sciences at the University of Manchester. They discuss how immunosuppressants could promote human hair growth and treat hair loss and consider how the immune system is involved in hair cycling. They also discuss Dr Hawkshaw's current research into the effects of ultra-violet radiation on the skin. For more information on Dr Hawkshaw's research follow this link: https://www.research.manchester.ac.uk/portal/nathan.hawkshaw.html…
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1 Episode 97 - Dr Simon Mendez Ferrer - How can targeting where stem cells live help transplants? 12:37
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Today on SC@L digested PhD Student Dr Beibei Du speaks with Dr Simón Méndez-Ferrer, a Reader in Transfusion Medicine at the University of Cambridge. They discuss what controls blood stem cell behaviour, including whether you are awake or asleep. Simón also talks about how understanding what makes blood stem cells move can be used in stem cell transplants to treat blood cancers. For more information on Simón's research, follow this link: http://www.haem.cam.ac.uk/staff/senior-staff/dr-simon-mendez-ferrer/…
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1 Episode 96 - Dr David Willnow - How can we treat diabetes with liver cells? 13:46
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For this episode of SC@L we’ve given remote recording a go to keep producing the podcast on lockdown! PhD student Ana Maria Cujba interviews Dr David Willnow from the Spagnoli Group at the CSCRM. They discuss his research into how the pancreas develops in the embryo and how this will develop potential future therapies for diabetes with this knowledge, David’s involvement multidiciplinary Pan3dp initiative , and the challenges of the immune response to regenerative cell therapies. For more information on David's research and the Spagnoli Lab, follow this link: https://www.spagnolilab.org…
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1 Episode 95 - Prof Fiona Watt - "Everything I do is hard-wired with the scientific mind set" 12:03
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For this extra special episode of SC@L digested, we are joined by CSCRM Director and MRC Executive Chair Professor Fiona Watt! Her PhD student Dr Xinyi (Beibei) Du speaks to her about her career path, what factors have helped her on her journey to success, her experiences of being a prominent woman in science and how we can support women in science. For more information on Professor Watt’s research follow this link: https://www.kcl.ac.uk/people/fiona-watt…
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