Minocycline: A New Hope in Delirium Prevention for Critically Ill Patients?

Saving Lives Podcast: Critical Care w/eddyjoemd

In this episode of the Saving Lives Podcast, we discuss a recent randomized controlled trial exploring the use of minocycline to prevent delirium in critically ill patients. The study reveals that minocycline may significantly reduce delirium incidence and hospital mortality, offering a promising new pharmacologic approach.

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Citation

Dal-Pizzol F, Coelho A, Simon CS, Michels M, Corneo E, Jeremias A, Damásio D, Ritter C. Prophylactic Minocycline for Delirium in Critically Ill Patients: A Randomized Controlled Trial. Chest. 2024 May;165(5):1129-1138. doi: 10.1016/j.chest.2023.11.041. Epub 2023 Dec 1. PMID: 38043911.