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04_08 Metastatic Renal Cell Carcinoma
Manage episode 432118872 series 3335024
1. Historical Approach (cytoreduction, IFN-a, sunitinib
2. Prognostic risk scores
3. Evidence for modern doublet regimens
4. Later line therapy
Citations
As always, citations, and sources include education from our respective training programs, the Devita textbook, and Uptodate.com. We highly encourage review of guidelines published by ASCO, ESMO and other organizations local to your practice.
DeVita, Vincent T., Jr., Theodore S. Lawrence, and Steven A. Rosenberg. Devita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology. 10th edition. Philadelphia: Wolters Kluwer, 2015.
Uptodate.com Waltham, MA: Wolters Kluwer.
- Flanigan RC et al. J Urol. 2004;171(3):1071-6. doi:10.1097/01.ju0000110610.61545.ae
- Bex A et al. JAMA Oncology. 2019;5(2):164-170. doi:10.1001/jamaoncol.2018.5545
- Mejean A et al. NEJM. 2018;379:417-427. doi:10.1056/NEJMoa1803675
- Motzer RJ et al. NEJM. 2007;356:115-124. doi:10.1056/NEJMoa065044
- Rini BI et al. NEJM. 2019;380:1116-1127. doi:10.1056/NEJMoa1816714
- Rini BI et al. JCO. 2023;41(17 Supp). doi:10.1200/JCO.2023.41.17_suppl.LBA4501
- Kartolo et al. Urology. 2021;157:8-14. doi:10.1016/j.urology.2021.08.023
- Motzer RJ et al. NEJM. 2018;378:1277-1290. doi:10.1056/NEJMoa1712126
- Motzer R et al. NEJM. 2021;384:1289-1300. doi:10.1056/NEJMoa2035716
- Albiges L et al. Ann Oncol. 2023;34(2 Supp):S1329-S1330. doi:10.1016/j.annonc.2023.10.090
- Jonasch E. ASCO Annual Meeting presented May 31, 2024 in Chicago, IL
Disclosures
Talking about Tumors with Ryan and Ryann is not medical advice. We have received no funding in relation to the information discussed within this episode and have no financial conflicts of interest to disclose. All opinions are those of whoever stated them. We have compiled this podcast to serve as an introduction to the field of medical oncology for post-graduate trainees interested in the topic.
Tags
Hematology/Oncology, evidence based medicine, education, chemotherapy, immunotherapy, medical oncology
49 פרקים
04_08 Metastatic Renal Cell Carcinoma
Talking About Tumors with Ryann and Ryan - A medical oncology podcast
Manage episode 432118872 series 3335024
1. Historical Approach (cytoreduction, IFN-a, sunitinib
2. Prognostic risk scores
3. Evidence for modern doublet regimens
4. Later line therapy
Citations
As always, citations, and sources include education from our respective training programs, the Devita textbook, and Uptodate.com. We highly encourage review of guidelines published by ASCO, ESMO and other organizations local to your practice.
DeVita, Vincent T., Jr., Theodore S. Lawrence, and Steven A. Rosenberg. Devita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology. 10th edition. Philadelphia: Wolters Kluwer, 2015.
Uptodate.com Waltham, MA: Wolters Kluwer.
- Flanigan RC et al. J Urol. 2004;171(3):1071-6. doi:10.1097/01.ju0000110610.61545.ae
- Bex A et al. JAMA Oncology. 2019;5(2):164-170. doi:10.1001/jamaoncol.2018.5545
- Mejean A et al. NEJM. 2018;379:417-427. doi:10.1056/NEJMoa1803675
- Motzer RJ et al. NEJM. 2007;356:115-124. doi:10.1056/NEJMoa065044
- Rini BI et al. NEJM. 2019;380:1116-1127. doi:10.1056/NEJMoa1816714
- Rini BI et al. JCO. 2023;41(17 Supp). doi:10.1200/JCO.2023.41.17_suppl.LBA4501
- Kartolo et al. Urology. 2021;157:8-14. doi:10.1016/j.urology.2021.08.023
- Motzer RJ et al. NEJM. 2018;378:1277-1290. doi:10.1056/NEJMoa1712126
- Motzer R et al. NEJM. 2021;384:1289-1300. doi:10.1056/NEJMoa2035716
- Albiges L et al. Ann Oncol. 2023;34(2 Supp):S1329-S1330. doi:10.1016/j.annonc.2023.10.090
- Jonasch E. ASCO Annual Meeting presented May 31, 2024 in Chicago, IL
Disclosures
Talking about Tumors with Ryan and Ryann is not medical advice. We have received no funding in relation to the information discussed within this episode and have no financial conflicts of interest to disclose. All opinions are those of whoever stated them. We have compiled this podcast to serve as an introduction to the field of medical oncology for post-graduate trainees interested in the topic.
Tags
Hematology/Oncology, evidence based medicine, education, chemotherapy, immunotherapy, medical oncology
49 פרקים
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×![Talking About Tumors with Ryann and Ryan - A medical oncology podcast podcast artwork](/static/images/64pixel.png)
![Talking About Tumors with Ryann and Ryan - A medical oncology podcast podcast artwork](/static/images/64pixel.png)
![Talking About Tumors with Ryann and Ryan - A medical oncology podcast podcast artwork](/static/images/64pixel.png)
![Talking About Tumors with Ryann and Ryan - A medical oncology podcast podcast artwork](/static/images/64pixel.png)
1 04_08 Metastatic Renal Cell Carcinoma 24:16
![Talking About Tumors with Ryann and Ryan - A medical oncology podcast podcast artwork](/static/images/64pixel.png)
1 04_07 Localized Renal Cell Carcinoma 25:15
![Talking About Tumors with Ryann and Ryan - A medical oncology podcast podcast artwork](/static/images/64pixel.png)
1 04_06 Metastatic Urothelial Cancer 24:33
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1 04_05 Muscle Invasive Bladder Cancer 29:16
![Talking About Tumors with Ryann and Ryan - A medical oncology podcast podcast artwork](/static/images/64pixel.png)
1 01_14 Ampullary Carcinoma (Mini Discussion) 10:59
![Talking About Tumors with Ryann and Ryan - A medical oncology podcast podcast artwork](/static/images/64pixel.png)
1 04_04 Castrate Resistant Metastatic Prostate Cancer 24:50
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1 04_03 Metastatic Castrate Sensitive Prostate Cancer 29:02
![Talking About Tumors with Ryann and Ryan - A medical oncology podcast podcast artwork](/static/images/64pixel.png)
1 04_02 Adjuvant Options for Prostate Cancer 28:41
![Talking About Tumors with Ryann and Ryan - A medical oncology podcast podcast artwork](/static/images/64pixel.png)
1 04_01 Fundamentals of Localized Prostate Cancer 31:59
![Talking About Tumors with Ryann and Ryan - A medical oncology podcast podcast artwork](/static/images/64pixel.png)
1 03_13 Head and Neck Cancer – Locally advanced and metastatic 37:18
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1 03_12 Head and Neck Cancer – Background and adjuvant considerations 23:28
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1 03_11 Mesothelioma and a bit of Large Cell Neuroendocrine Carcinoma 29:40
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