🧬Chris Moxham - Transcripta Bio - Part 3 | Embracing the Startup Challenge | Mastering Science-to-Business Communication | Building a Scalable Discovery Engine | Leveraging AI & Genetics in Drug Development

The Biotech Startups Podcast

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Part 3 of 4: Jon Chee hosts Chris Moxham, Co-Founder, CEO, and CSO of Transcripta Bio—a pioneering biotech company accelerating drug discovery to improve lives worldwide.

With a PhD in Molecular and Cellular Pharmacology from Stony Brook University and over 25 years in drug discovery, Chris brings a wealth of experience. During his two-decade tenure at Eli Lilly, he advanced over 10 molecules into clinical trials across multiple therapeutic areas, spanning both small and large molecule modalities.

Chris’s deep expertise and dedication to scientific innovation and team development offer invaluable insights for aspiring biotech leaders.

Join us this week to hear about:

• Chris’ transition from Eli Lilly to the startup world, embracing the excitement and uncertainty of a smaller company.
• Navigating investor relations and honing the skill of translating science into business language.
• Developing Transcripta Bio’s discovery engine, a scalable approach to drug discovery.
• Leveraging AI, genetics, and high-throughput data to reduce failure points in drug development.

Please enjoy Jon’s conversation with Chris Moxham.

Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994

Find Our Guest, Chris Moxham, at these links:

https://www.linkedin.com/in/christopher-moxham-b8867011/

https://www.transcriptabio.com/

Find Our Host, Jon Chee, at these links:

https://www.linkedin.com/in/jonchee

https://www.excedr.com

Excedr Socials & Website

LinkedIn: https://www.linkedin.com/company/excedr/

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Podcast Website: https://www.thebiotechstartupspodcast.com/

Enriched Notes:

Topics Mentioned:

Wyeth Labs: https://en.wikipedia.org/wiki/Wyeth

Eli Lilly & Company: https://www.lilly.com/

Fulcrum Therapeutics: https://www.fulcrumtx.com/

Transcripta Bio: https://www.transcriptabio.com/

Transcripta Bio’s Discovery Engine: https://www.transcriptabio.com/what-we-do

How to Start a Lab: https://www.excedr.com/blog/how-to-start-a-lab

How Much Does Lab Space Cost? https://www.excedr.com/blog/how-much-does-lab-space-cost

Biotech Startup Support: https://www.excedr.com/resources-category/biotech-startup-support

Investor & Founder Expectations: https://www.excedr.com/resources/investor-founder-expectations

Generative AI in Drug Discovery: https://www.forbes.com/sites/bernardmarr/2024/06/19/how-generative-ai-is-accelerating-drug-discovery/

People Mentioned:

Robert Gould: https://www.linkedin.com/in/robertjgouldfulcrum/

Timestamps:

00:00 Intro

02:12 Chris's Transition to Fulcrum: moving from Big Pharma to a smaller Biotech

03:42 Mastering investor relations and learning to translate science into business language

06:07 Lessons from an IPO and building rapport with investors

08:00 Life as CSO of a Public Company and the importance of media training

14:57 Building Transcripta Bio’s Discovery Engine and repurposing to accelerate value creation

20:08 Leveraging AI in drug discovery and creating new opportunities in CNS and oncology

23:52 Scaling drug discovery innovation and building the Drug-Gene Atlas

25:09 Outro

The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.