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Is Prazosin Effective for PTSD? Depends on the Inclusion Criteria
Manage episode 291158542 series 2818069
The article we discuss is MA Raskind et al. Trial of Prazosin for Post-Traumatic Stress Disorder in Military Veterans. New England Journal of Medicine 2018; 378(6):507-517
For an example of an earlier study that DID find benefit of prazosin for PTSD, check out Raskind, MA et al. A Trial of Prazosin for Combat Trauma PTSD with Nightmares in Active-Duty Soldiers Returned from Iraq and Afghanistan. Am J Psychiatry 2013; 170: 1003-1010.
Recent meta-analyses of the efficacy of prazosin for PTSD can be found here and here.
A brief review on the ethical principles of equipoise in research.
11 פרקים
Manage episode 291158542 series 2818069
The article we discuss is MA Raskind et al. Trial of Prazosin for Post-Traumatic Stress Disorder in Military Veterans. New England Journal of Medicine 2018; 378(6):507-517
For an example of an earlier study that DID find benefit of prazosin for PTSD, check out Raskind, MA et al. A Trial of Prazosin for Combat Trauma PTSD with Nightmares in Active-Duty Soldiers Returned from Iraq and Afghanistan. Am J Psychiatry 2013; 170: 1003-1010.
Recent meta-analyses of the efficacy of prazosin for PTSD can be found here and here.
A brief review on the ethical principles of equipoise in research.
11 פרקים
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