#17 Journal Round Up July '20// UGI bleeds & Tranexamic acid + Theophylline in acute stroke + Probiotics for all (?) + Coffee time....+ putting the ash in wash

JournalSpotting

Are you trying to keep up with the latest medical literature but your journals keep getting blown away by the industrial fan you’ve bought to try and survive this sweaty heat wave? Your ears are in the right place! In this months episode:
...Tranexamic acid in UGI bleeding: more harm than good?...(04:35)
HALT-IT Trial Collaborators. “Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial.” Lancet (London, England) vol. 395,10241 (2020): 1927-1936. doi:10.1016/S0140-6736(20)30848-5
...Cocoa beans in acute ischaemic stroke?...(08:15)
Modrau, Boris et al. “Theophylline as an Add-On to Thrombolytic Therapy in Acute Ischemic Stroke: A Randomized Placebo-Controlled Trial.” Stroke vol. 51,7 (2020): 1983-1990.
...Ticagrelor for stroke prevention?...(12:40)
Johnston, S Claiborne et al. “Ticagrelor and Aspirin or Aspirin Alone in Acute Ischemic Stroke or TIA.” The New England journal of medicine vol. 383,3 (2020): 207-217.
...Probiotics for your mood?... (16:28)
Noonan S, Zaveri M, Macaninch E, et al Food & mood: a review of supplementary prebiotic and probiotic interventions in the treatment of anxiety and depression in adults BMJ Nutrition, Prevention & Health 2020
...Probiotics in care homes... (22:15)
Butler, Christopher C et al. “Effect of Probiotic Use on Antibiotic Administration Among Care Home Residents: A Randomized Clinical Trial.” JAMA vol. 324,1 (2020): 47-56.
...Tofu to reduce mortality?... (25:11)
Cai, Xiaoyan et al. “Association between prediabetes and risk of all cause mortality and cardiovascular disease: updated meta-analysis.” BMJ (Clinical research ed.) vol. 370 m2297. 15 Jul. 2020,
...Coffee time: the facts and myths... (29:16)
van Dam, Rob M et al. “Coffee, Caffeine, and Health.” The New England journal of medicine vol. 383,4 (2020): 369-378.
...Does MTX actually cause ILD?...(33:15)
Juge, Pierre-Antoine et al. “Methotrexate and rheumatoid arthritis associated interstitial lung disease.” The European respiratory journal, 2000337. 9 Jul. 2020,
JOURNALBITES (38:13)
Vitamin D & diabetes prevention
An app for cardiac arrest
Noradrenaline dysregulates the immune response
AI & Skin disease

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