From Our Neurons to Yours crisscrosses scientific disciplines to bring you to the frontiers of brain science. Coming to you from the Wu Tsai Neurosciences Institute at Stanford University, we ask leading scientists to help us understand the three pounds of matter within our skulls and how new discoveries, treatments, and technologies are transforming our relationship with the brain. Finalist for 2024 Signal Awards!
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The BRAIN Initiative: the national vision for the future of neuroscience is now in doubt | Bill Newsome
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Earlier this year, President Obama's signature BRAIN Initiative, which has powered advances in neuroscience for the past 10 years, had its budget slashed by 40%. Over the past decade, the BRAIN Initiative made roughly $4 billion in targeted investments in more than 1500 research projects across the country and has dramatically accelerated progress …
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The cannabinoids within: how marijuana hijacks an ancient signaling system in the brain | Ivan Soltesz
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Given the widespread legalization of cannabis for medical and recreational uses, you'd think we'd have a better understanding of how it works. But ask a neuroscientist exactly how cannabinoid compounds like THC and CBD alter our perceptions or lead to potential medical benefits, and you'll soon learn just how little we know. We know that these mole…
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Memory Palaces: the science of mental time travel and the brain's GPS system | Lisa Giocomo (Re-release)
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Today we are re-releasing an episode we did last year with Stanford neurobiologist Lisa Giocomo exploring the intersection of memory, navigation and the boundaries we create between ourselves and the world around us. This episode was inspired by the idea of memory palaces. The idea is simple: Take a place you're very familiar with, say the house yo…
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Why new Alzheimer's drugs don't work | Mike Greicius, Stanford University School of Medicine
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In the past few years, Big Pharma has released not one, but three new treatments for Alzheimer’s disease. Aducanemab (2021), Lecanemab (2023), and Donanemab (2024), are the first treatments to effectively clear the brain of amyloid plaques — the sticky protein clumps whose build-up in the brain has defined the disease for decades. The problem? They…
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Depression's distinctive fingerprints in the brain | Leanne Williams, Stanford University
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Getting help for depression can be like purgatory. Setting aside for a moment the stigma and other barriers to seeking treatment in the first place, finding the right combination of medication and/or therapy can be a months- or years-long process of trial and error. And for about one third of people, nothing seems to work. Today we're talking with …
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How the brain helps cancers grow | Michelle Monje
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Today, we're talking with Stanford neuro-oncologist, Michelle Monje. This is actually the third time we've had Michelle on the show, in part because she's been a pioneer of three exciting frontiers in neuroscience — so far! This week, we're going to talk about cancer neuroscience. Michelle founded this new field with her discovery that deadly brain…
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Unraveling Timothy Syndrome: the new science of human brain development | Sergiu Pasca
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This week on From Our Neurons to Yours, we're talking about using new techniques for growing human brain tissue in the lab to solve a rare neurological disorder. Host Nicholas Weiler sits down with Sergiu Pasca an innovative Stanford scientist who has developed groundbreaking technologies to grow human brain tissue in the lab, creating "organoids" …
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How VR could help treat depression with "radical behaviorist" Dr. Kim Bullock
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Today, we're going to talk about virtual reality and how it could be used to treat depression. We're talking with psychiatrist Kim Bullock, the founding director of Stanford's Neurobehavioral Clinic and Virtual Reality & Immersive Technologies (VRIT) program. Dr. Bullock — a physician certified in Neuropsychiatry, Psychiatry, and Lifestyle Medicine…
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Electronic skin and the future of wearable technology | Zhenan Bao
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The skin is full of contradictions. It’s soft and sensitive, but also tough and resilient, even self-healing. It’s both the barrier that protects us from infections and our most intimate connection with the outside world. Today’s guest, Zhenan Bao, has spent the last two decades reverse engineering the skin’s many remarkable properties in order to …
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How a new kind of brain plasticity could help make sense of addiction | Michelle Monje and Rob Malenka
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This week, we're diving into recent research that sheds light on a new form of brain plasticity involving changes in the insulation of nerve fibers — called myelin. It turns out that myelin plasticity is implicated in a number of serious conditions, from epilepsy to drug abuse and addiction. We're excited to bring back two previous guests on the sh…
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Our plastic brains: learning, memory and aging with the one and only Carla Shatz (Rerelease)
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-- We're re-releasing our conversation with Carla Shatz, one of our favorites from the archive, which comes up all the time on the show in the context of brain plasticity and aging. Enjoy, and see you next time! -NW -- When we're kids, our brains are amazing at learning. We absorb information from the outside world with ease, and we can adapt to an…
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Hi everyone — quick programming announcement. As we head into summer, we'll be moving to an every-other-week cadence as we prepare more conversations from the frontiers of neuroscience. I'm very excited about what we're working on for you, so stay tuned! In the meantime, we'd love to hear from you! Email us at neuronspodcast@stanford.edu with your …
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Neuroscience and AI: What artificial intelligence teaches us about the brain (and vice versa) | Surya Ganguli
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The powerful new generation of AI tools that has come out over the past few years — DALL-E, ChatGPT, Claude, Gemini, and the rest — have blown away our old ideas about what AI can do and raised questions about what it means for computers to start acting... intelligent? This week, we ask what the rise of these systems might teach us about our own bi…
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How we remember, why we forget | Anthony Wagner
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At some point in our lives, we all struggle with memory — learning a new name, remembering that book you were reading just yesterday or that word on the tip of your tongue. So what can neuroscience teach us about why we remember, why we forget, and how we might even improve our memories? To answer this question, I spoke with neuroscientist Anthony …
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Psychedelics Part 2: How do drugs alter our perceptions? | Boris Heifets
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Today, we're going to talk about how psychedelics alter our perception of reality and what that says about... reality! Welcome to part two of our conversation with Stanford anesthesiologist and psychedelics researcher Boris Heifets! Last time, we talked with Boris about the question of why psychedelics help people with mental health disorders. This…
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Psychedelics, placebo, and anesthetic dreams | Boris Heifets (part 1)
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Psychedelics are a hot topic in psychiatry today. They’re producing dramatic reversals for patients with severe depression, PTSD, and other mental health conditions. But scientists still have fundamental questions about why these drugs are so effective. For example, is the "trip" even necessary? Some think it is not and are working to design drugs …
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Why our brains are bad at climate change | Nik Sawe
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This week on From Our Neurons to Yours, we're talking about the neuroscience of climate change with neuroeconomist Nik Sawe. If you follow the science or the news, you know how big of a risk climate change is. Storms, coastal flooding, heat waves, extinctions, mass migration — the list goes on. But — as you can probably also appreciate — it’s reall…
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Famous & Gravy: Mind Traveler | Oliver Sacks
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This week we’re doing something a little different. My good friend Michael Osborne, who produces this show also has his own podcast, called Famous & Gravy – Life Lessons from Dead Celebrities. I recently guest-hosted an episode about one of my all time scientific and writerly heros, Oliver Sacks, which we're releasing for both our audiences. I hope…
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The clocks in your body | Tony Wyss-Coray
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Today: the clocks in your body. We're talking again this week with Tony Wyss-Coray, the director of the Knight Initiative for Brain Resilience here at Wu Tsai Neuro. Last year, we spoke with Tony about the biological nature of the aging process. Scientists can now measure signs of aging in the blood, and can in some cases slow or reverse the aging …
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Redefining Parkinson's Disease | Kathleen Poston
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Today on the show, a new understanding of Parkinson's disease. Parkinson's disease is one of the most common neurodegenerative disorders — right after Alzheimer's disease. It's familiar to many as a movement disorder: people with the disease develop difficulties with voluntary control of their bodies. But the real story is much more complicated. Th…
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This week on From Our Neurons to Yours, we sit down with Stanford neurobiologist Lisa Giocomo to explore the intersection of memory and navigation. This episode was inspired by the idea of memory palaces. The idea is simple: Take a place you're very familiar with, say the house you grew up in, and place information you want to remember in different…
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OCD & Ketamine | Carolyn Rodriguez
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In this episode of "From Our Neurons to Yours," we're taking a deep dive into the neuroscience of obsessive-compulsive disorder (OCD) and the recent discovery that the anesthetic ketamine can give patients a week-long "vacation" from the disorder after just one dose. Join us as we chat with Dr. Carolyn Rodriguez, a leading expert in the field, who …
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Why we do what we do | Neir Eshel
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Welcome to "From Our Neurons to Yours," from the Wu Tsai Neurosciences Institute at Stanford University. Each week, we bring you to the frontiers of brain science — to meet the scientists unlocking the mysteries of the mind and building the tools that will let us communicate better with our brains. This week, we're tackling a BIG question in neuros…
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Brain-Machine Interfaces | Jaimie Henderson
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Imagine being trapped in your own body, unable to move or communicate effectively. This may seem like a nightmare, but it is a reality for many people living with brain or spinal cord injuries. Join us as we talk with Jaimie Henderson, a Stanford neurosurgeon leading groundbreaking research in brain-machine interfaces. Henderson shares how multiple…
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An electrical storm in the brain | Fiona Baumer
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Imagine an electrical storm in your brain, a power surge that passes through delicately wired neural circuits, making thousands of cells all activate at once. Depending on where it starts and where it travels in the brain, it could make your muscles seize up. It could create hallucinatory visions or imaginary sounds. It could evoke deep anxiety or …
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Seeing sound, tasting color | David Eagleman
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Imagine Thursday. Does Thursday have a color? What about the sound of rain — does that sound taste like chocolate? Or does the sound of a saxophone feel triangular to you? For about 3% of the population, the sharp lines between our senses blend together. Textures may have tastes, sounds, shapes, numbers may have colors. This sensory crosstalk is ca…
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Why sleep keeps us young | Luis de Lecea
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Welcome back, neuron lovers! In this week's episode of From Our Neurons to Yours, we're talking about the neuroscience of sleep. Why is slumber so important for our health that we spend a third of our lives unconscious? Why does it get harder to get a good night's sleep as we age? And could improving our beauty rest really be a key to rejuvenating …
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Where ant colonies keep their brains | Deborah Gordon
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Welcome back to "From Our Neurons to Yours," a podcast from the Wu Tsai Neurosciences Institute at Stanford University. In this episode, we explore the collective intelligence of ant colonies with Deborah Gordon, a professor of biology at Stanford, an expert on ant behavior, and author of a new book, The Ecology of Collective Behavior. We discuss h…
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Why we get dizzy | Kristen Steenerson
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Welcome back to "From Our Neurons to Yours," a podcast where we criss-cross scientific disciplines to take you to the frontiers of brain science. This week, we explore the science of dizziness with Stanford Medicine neurologist Kristen Steenerson, MD, who treats patients experiencing vertigo and balance disorders. In our conversation, we'll see tha…
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How we understand each other | Laura Gwilliams
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Welcome back to our second season of "From Our Neurons to Yours," a podcast where we criss-cross scientific disciplines to take you to the cutting edge of brain science. In this episode, we explore how sound becomes information in the human brain, specifically focusing on how speech is transformed into meaning. Our guest this week is Neuro-linguist…
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Exercise and the brain | Jonathan Long
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We all know exercise has all sorts of benefits beyond just making us stronger and fitter. It lowers and inflammation. It buffers stress and anxiety. It clarifies our thinking. In fact, regular exercise is one of the few things we know with reasonable confidence can help extend our healthy lifespan. But for all the evidence of the benefits of exerci…
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Aging and Brain Plasticity | Carla Shatz
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When we're kids, our brains are amazing at learning. We absorb information from the outside world with ease, and we can adapt to anything. But as we age, our brains become a little more fixed. Our brain circuits become a little less flexible. You may have heard of a concept called neuroplasticity, our brain's ability to change or rewire itself. Thi…
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Brain stimulation & "psychiatry 3.0" | Nolan Williams
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Transcranial magnetic stimulation (TMS) is a technology that uses magnetic fields to stimulate or suppress electrical activity in brain circuits. It's part of a transformation in how psychiatrists are thinking about mental health disorders that today's guest calls psychiatry 3.0. Nolan Williams has recently pioneered a new form of TMS therapy that …
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One of the strangest and most disconcerting things about the COVID 19 pandemic has been the story of long COVID. Many COVID long-haulers have continued experiencing cognitive symptoms long after their initial COVID infection — loss of attention, concentration, memory, and mental sharpness — what scientists are calling "brain fog". For some patients…
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Assembling the brain | Sergiu Pasca
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Nearly one in five Americans lives with a mental illness. Unfortunately there’s a limited set of options for treating psychiatric disorders. One reason for that is that these disorders are still defined based on people’s behavior or invisible internal states — things like depressed mood or hallucinations. But of course, all our thoughts and behavio…
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Parenting Lessons from Frogs and Spiders | Lauren O'Connell
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Today we’re going to talk about frogs — and spiders — as parents. What today’s show is really about is “pair bonding” — that’s the scientific term for the collaborative bonds that form between two parents — as well as the bonds between parents and their offspring. It turns out that if you look across the animal kingdom, strong family bonds are way …
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Recently on the show, we had a conversation about the possibility of creating artificial vision with a bionic eye. Today we're going to talk about technology to enhance another sense, one that often goes underappreciated, our sense of touch. We humans actually have one of the most sensitive senses of touch on the planet. Just in the tip of your fin…
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Brain Rejuvenation | Tony Wyss-Coray
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Hi listeners, we're shifting to a biweekly release schedule after this episode. See you in a couple weeks! --- Most of us probably know someone who developed Alzheimer’s disease or another form of dementia as they got older. But you probably also know someone who stayed sharp as a tack well into their 80s or 90s. Even if it’s a favorite TV actor, l…
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Building a bionic eye | EJ Chichilnisky
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We take this for granted, but our eyes are amazing. They're incredible. We process the visual world so automatically and so instantaneously, we forget how much work our eyes and our brains are doing behind the scenes, taking in light through the eyeball, transforming light into electrical signals in the retina, packaging up all that information, an…
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Respect your Biological Clock | Erin Gibson
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We've probably all heard of circadian rhythms, the idea that our bodies have biological clocks that keep track of the daily cycle, sunrise to sunset. Maybe we've even heard that it's these biological rhythms that get thrown off when we travel across time zones or after daylight savings. So on one hand, it's cool that our body keeps track of what ti…
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Is Addiction a Disease? | Keith Humphreys
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What makes addiction a disease? I think we all know at this point that addiction is another major epidemic that is sweeping our country and the world, but there are few topics that are more misunderstood than addiction. In fact, some people question whether addiction is even truly a disease. To delve into this question of why neuroscientists and he…
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Your gut - the second brain? | Julia Kaltschmidt
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You may have heard the idea that the gut is the second brain, but what does that really mean? Maybe it has to do with the fact that there are something like 100 to 600 million neurons in your gut. That's a lot of neurons. That's about as many as you'd find in the brain of say, a fruit bat, or an ostrich, or a Yorkshire Terrier. And it turns out, th…
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The Octopus Brain | Ernie Hwaun & Matt McCoy
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What can octopus and squid brains teach us about intelligence? One of the incredible things about octopus's is that not only do they have an advanced intelligence that lets them camouflage themselves, use tools and manipulate their environments and act as really clever hunters in their ecosystems, they do this with a brain that evolved essentially …
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The Mystery of Migraines | Gabriella Muwanga
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If you've ever had a migraine, you know that the symptoms — splitting headache, nausea, sensitivity to light — mean you're going to want to spend some time in bed, in a dark room. Migraines are flat out debilitating, and the statistics back this up. Migraines are the third most common neurological disorder. They affect as many as a billion people a…
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Psychedelics and Empathy | Rob Malenka
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Why are psychiatrists taking a fresh look at MDMA? Recently, there's been growing excitement in the scientific community about revisiting the potential medical benefits of psychedelic drugs that have been off limits for decades. Scientists are discovering or rediscovering applications of psilocybin, LSD, MDMA, and other compounds for treating peopl…
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Announcing: From Our Neurons to Yours!
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Announcing: From our Neurons to Yours, the new podcast from the Wu Tsai Neurosciences Institute at Stanford University. On this show, we criss-cross scientific disciplines to bring you to the frontiers of brain science, one simple question at a time. Send us a text! Thanks for listening! If you're enjoying our show, please take a moment to give us …
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